Foerster M H, Bornfeld N, Schulz U, Wessing A, Meyer-Schwickerath G
Graefes Arch Clin Exp Ophthalmol. 1986;224(4):336-40. doi: 10.1007/BF02150026.
The results of local beta ray radiation of 295 eyes containing a uveal melanoma (including 74 melanomas of the anterior choroid and ciliary body) are presented with special respect to the complications of treatment. The most frequent complications were radiation retinopathy and optic neuropathy. Complications known to occur from other radiation methods, such as dry eye syndrome, loss of cilia, and scleral necrosis, did not occur in our series. The incidence of radiation cataract, as compared to the treatment with 60Co plaques, was lower in our series. An average of 700 Gy delivered to the scleral base of the tumor was needed for uveal melanomas which could be destroyed. This radiation dose resulted in a 10% incidence of radiation retinopathy.
本文呈现了295只患有葡萄膜黑色素瘤眼睛（包括74例脉络膜前部和睫状体黑色素瘤）的局部β射线放射治疗结果，特别关注了治疗并发症。最常见的并发症是放射性视网膜病变和视神经病变。其他放射治疗方法已知会出现的并发症，如干眼综合征、睫毛脱落和巩膜坏死，在我们的研究系列中并未出现。与60钴敷贴治疗相比，我们研究系列中放射性白内障的发生率较低。对于可被摧毁的葡萄膜黑色素瘤，平均需要向肿瘤巩膜基底部给予700戈瑞的放射剂量。该放射剂量导致放射性视网膜病变的发生率为10%。
