V A Muralidhar, C P Madhu, S Sudhir, Srinivasarangan Madhu
Resident, Department of General Surgery, JSS Medical College , Mysore, Karnataka, India .
Professor and Unit Head, Department of General Surgery, JSS Medical College , Mysore, Karnataka, India .
J Clin Diagn Res. 2014 Dec;8(12):NC01-3. doi: 10.7860/JCDR/2014/8609.5229. Epub 2014 Dec 5.
Despite advances in diagnosis, management and critical care of patients with peritonitis due to hollow viscus perforation, prognosis remains poor. Early assessment by scoring systems will influence the management and prognosis.
Evaluation of Mannheim Peritonitis Index (MPI) score for predicting the outcome in patients with peritonitis.
Prospective study of 50 patients admitted and operated for peritonitis in JSS Medical College Hospital. The structured scoring system i.e. MPI was applied along with other clinical and biochemical parameters recorded in pre-structured proforma. Data was analysed for predicting mortality and morbidity using EPI info and SPSS software.
The overall mortality and morbidity was 14% and 38% respectively. MPI scores of ≤ 20, 21-29, and ≥ 30 had a mortality of 5%, 14%, and 50% respectively. MPI score of 25 had highest sensitivity of 72.09% and specificity of 71.43% in predicting mortality, 80.65% sensitivity and 57.89% specificity for morbidity. MPI score of > 25 were associated with 6.45 times higher risk of mortality (p=0.03), 5.72 times higher risk of morbidity (p=0.005) compared to patients with MPI score ≤ 25.
MPI is disease specific, easy scoring system for predicting the mortality in patients with secondary peritonitis. Increasing scores are associated with poorer prognosis, needs intensive management and hence it should be used routinely in clinical practice.
尽管在因中空脏器穿孔导致的腹膜炎患者的诊断、治疗及重症监护方面取得了进展,但其预后仍然很差。通过评分系统进行早期评估将影响治疗和预后。
评估曼海姆腹膜炎指数(MPI)评分对腹膜炎患者预后的预测价值。
对在JSS医学院医院收治并接受腹膜炎手术的50例患者进行前瞻性研究。应用结构化评分系统即MPI,并在预先构建的表格中记录其他临床和生化参数。使用EPI info和SPSS软件分析数据以预测死亡率和发病率。
总体死亡率和发病率分别为14%和38%。MPI评分≤20、21 - 29及≥30的患者死亡率分别为5%、14%和50%。MPI评分为25时,预测死亡率的敏感性最高,为72.09%,特异性为71.43%;预测发病率的敏感性为80.65%,特异性为57.89%。与MPI评分≤25的患者相比,MPI评分>25的患者死亡风险高6.45倍(p = 0.03),发病风险高5.72倍(p = 0.005)。
MPI是一种针对疾病的、易于使用的评分系统,可用于预测继发性腹膜炎患者的死亡率。评分增加与预后较差相关,需要强化治疗,因此应在临床实践中常规使用。