黄色短杆菌中抗生素抗性突变体的诱导
Induction of mutants resistant to antibiotics in Brevibacterium flavum.
作者信息
Konícek J, Konícková-Radochová M, Rytír V
出版信息
Folia Microbiol (Praha). 1986;31(2):94-7. doi: 10.1007/BF02926825.
PMID:3710319
Abstract
The optimum conditions for the induction of mutants resistant to antibiotics in Brevibacterium flavum ATCC 14067 were determined. UV irradiation at the energy fluence of 6.5 kJ/m2 and N-methyl-N'-nitro-N-nitrosoguanidine (1 mg/mL) at pH 6.0 were used for the induction of mutants. Mutant strains resistant to rifampicin, oleandomycin, streptomycin and erythromycin were prepared.
摘要
确定了在黄色短杆菌ATCC 14067中诱导抗生素抗性突变体的最佳条件。使用能量通量为6.5 kJ/m2的紫外线照射和pH 6.0条件下的N-甲基-N'-硝基-N-亚硝基胍（1 mg/mL）来诱导突变体。制备了对利福平、竹桃霉素、链霉素和红霉素具有抗性的突变菌株。
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