Lebret Arnaud, Normand Valérie, Teixeira Costa Charlotte, Messager Ingrid, Berton Pauline, Brissonnier Mathieu, Nicolazo Théo, Boulbria Gwenaël
Porc.Spective Swine Vet Practice, ZA de Gohélève, 56920 Noyal-Pontivy, France.
Rezoolution Pig Consulting Services, ZA de Gohélève, 56920 Noyal-Pontivy, France.
Vet Sci. 2023 Apr 15;10(4):294. doi: 10.3390/vetsci10040294.
Data concerning PRRSV-1 vaccine virus strains dissemination within vaccinated sow herds are scarce. However, it is a big concern for swine practitioners when designing the PRRSV diagnostics strategy in vaccinated farms. At the same time, the possibility of vaccine virus transmission from sows to their offspring is important to have in mind in order to limit the risk of recombination between different PPRSV-1 modified live virus vaccine (MLV1) when both sows and piglets have to be vaccinated. This study was conducted in five PRRSV-stable breeding herds. The selected farms presented different characteristics regarding production parameters and biosecurity management practices in order to be, as much as possible, representative of French swine production herds. In four different batches following a sow mass vaccination with a PRRSV-1 modified live virus vaccine (ReproCyc PRRS EU, Boehringer Ingelheim, Ingelheim, Germany), we failed to detect the vaccine virus in due-to-wean piglets in all of the herds. This should mean that the dissemination of the vaccinal strain is a rare event, even just after a sow vaccination, at least for the vaccine tested in our study.
关于猪繁殖与呼吸综合征病毒1型（PRRSV-1）疫苗病毒株在接种疫苗的母猪群中传播的数据很少。然而，在为接种疫苗的猪场设计PRRSV诊断策略时，这是猪从业者非常关注的问题。同时，为了在母猪和仔猪都必须接种疫苗时限制不同PRRSV-1改良活病毒疫苗（MLV1）之间重组的风险，必须考虑疫苗病毒从母猪传播到其后代的可能性。本研究在五个PRRSV稳定的种猪场进行。所选猪场在生产参数和生物安全管理措施方面呈现出不同特点，以便尽可能代表法国养猪生产群。在用PRRSV-1改良活病毒疫苗（ReproCyc PRRS EU，德国勃林格殷格翰公司，英格尔海姆）对母猪进行大规模接种后的四个不同批次中，我们未能在所有猪群的待断奶仔猪中检测到疫苗病毒。这应该意味着疫苗株的传播是罕见事件，即使在母猪接种疫苗后不久，至少对于我们研究中测试的疫苗来说是这样。
