Grieshaber T L, Blakemore J C, Yaskulski S
J Am Vet Med Assoc. 1986 May 1;188(9):1053-4.
A Bichon Frise pup had congenital alopecia. Histologic evaluation revealed the absence of hair follicles, arector pili muscles, sebaceous glands, and sweat glands. Unlike previously described cases of congenital ectodermal defect, this alopecia was not associated with any color pattern; the pup was white until it was 4 months old, at which time normal black and brown pigmentation developed independently of the alopecic pattern.
一只比熊幼犬患有先天性脱发。组织学评估显示毛囊、竖毛肌、皮脂腺和汗腺均缺失。与先前描述的先天性外胚层缺陷病例不同,这种脱发与任何毛色模式均无关;这只幼犬在4个月大之前都是白色的,那时正常的黑色和棕色色素沉着独立于脱发模式而形成。