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胰十二指肠切除术的横向切口可减少伤口并发症:399例患者的单中心分析

Transverse Incision for Pancreatoduodenectomy Reduces Wound Complications: A Single-Center Analysis of 399 Patients.

作者信息

Junker Stefanie, Jacobsen Anne, Merkel Susanne, Denz Axel, Krautz Christian, Weber Georg F, Grützmann Robert, Brunner Maximilian

机构信息

Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, 91054 Erlangen, Germany.

出版信息

J Clin Med. 2023 Apr 10;12(8):2800. doi: 10.3390/jcm12082800.

DOI:10.3390/jcm12082800
PMID:37109136
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10143640/
Abstract

BACKGROUND

Even if the minimally invasive approach is advancing in pancreatic surgery, the open approach is still the standard for a pancreatoduodenectomy. There are two types of incisions used: the midline incision (MI) and transverse incision (TI). The aim of this study was to compare these two incision types, especially regarding wound complications.

METHODS

A retrospective review of 399 patients who underwent a pancreatoduodenectomy at the University Hospital Erlangen between 2012 and 2021 was performed. A total of 169 patients with MIs were compared with 230 patients with TIs, with a focus on postoperative fascial dehiscence, postoperative superficial surgical site infection (SSSI) and the occurrence of incisional hernias during follow-up.

RESULTS

Postoperative fascial dehiscence, postoperative SSSI and incisional hernias occurred in 3%, 8% and 5% of patients, respectively. Postoperative SSSI and incisional hernias were significantly less frequent in the TI group (SSI: 5% vs. 12%, = 0.024; incisional hernia: 2% vs. 8%, = 0.041). A multivariate analysis confirmed the TI type as an independent protective factor for the occurrence of SSSI and incisional hernias (HR 0.45 (95% CI = 0.20-0.99), = 0.046 and HR 0.18 (95% CI = 0.04-0.92), = 0.039, respectively).

CONCLUSION

Our data suggest that the transverse incision for pancreatoduodenectomy is associated with reduced wound complications. This finding should be confirmed by a randomized controlled trial.

摘要

背景

尽管微创方法在胰腺手术中不断发展,但开放手术仍是胰十二指肠切除术的标准术式。常用的切口有两种:中线切口(MI)和横切口(TI)。本研究的目的是比较这两种切口类型,尤其是伤口并发症方面。

方法

对2012年至2021年在埃尔朗根大学医院接受胰十二指肠切除术的399例患者进行回顾性研究。将169例采用中线切口的患者与230例采用横切口的患者进行比较,重点关注术后筋膜裂开、术后浅表手术部位感染(SSSI)以及随访期间切口疝的发生情况。

结果

术后筋膜裂开、术后SSSI和切口疝的发生率分别为3%、8%和5%。横切口组术后SSSI和切口疝的发生率明显较低(SSSI:5%对12%,P = 0.024;切口疝:2%对8%,P = 0.041)。多因素分析证实横切口类型是SSSI和切口疝发生的独立保护因素(HR 0.45(95%CI = 0.20 - 0.99),P = 0.046;HR 0.18(95%CI = 0.04 - 0.92),P = 0.039)。

结论

我们的数据表明,胰十二指肠切除术采用横切口与伤口并发症减少相关。这一发现应通过随机对照试验加以证实。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ea7/10143640/6fcee6039a9b/jcm-12-02800-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ea7/10143640/6fcee6039a9b/jcm-12-02800-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ea7/10143640/6fcee6039a9b/jcm-12-02800-g001.jpg

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Long-Term Surgical Complications After Pancreatoduodenectomy: Incidence, Outcomes, and Risk Factors.胰十二指肠切除术后的长期手术并发症:发生率、结局和危险因素。
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