Posa Alessandro, Tenore Lorenzo, Barbieri Pierluigi, Mazza Giulia, Sala Evis, Iezzi Roberto
Department of Diagnostic Imaging, Oncologic Radiotherapy and Hematology, A. Gemelli University Hospital Foundation IRCCS, L.go A. Gemelli 8, 00168 Rome, Italy.
Istituto di Radiodiagnostica, Catholic University of the Sacred Heart, L.go F. Vito 1, 00168 Rome, Italy.
Life (Basel). 2023 Mar 24;13(4):868. doi: 10.3390/life13040868.
Transjugular intrahepatic porto-systemic shunt (TIPSS) is an interventional radiology procedure whose aim is to create artificial communication between the portal and the hepatic blood flow in order to reduce the pressure gradient in portal hypertension. The indications to perform a TIPSS procedure can be framed in an elective or emergency setting: refractory ascites to diuretic therapy and secondary prophylaxis of variceal hemorrhage are the most frequent reasons for executing a TIPSS in an election context, while acute uncontrolled variceal bleeding is the principal indication that a TIPSS needs to be performed in an emergency setting. In recent years, the role of the TIPSS has been redefined for several conditions, such as ectopic varices, portal vein thrombosis, Budd-Chiari syndrome, hepatic veno-occlusive disease, and many others. This review aims to perform a deep analysis of when and why a TIPSS procedure should be carried out in an emergency, pointing out the related most common technical difficulties and complications.
经颈静脉肝内门体分流术(TIPSS)是一种介入放射学手术,其目的是在门静脉和肝血流之间建立人工通道,以降低门静脉高压中的压力梯度。进行TIPSS手术的适应证可分为择期或急诊情况:对利尿治疗无效的腹水和静脉曲张出血的二级预防是在择期情况下进行TIPSS的最常见原因,而急性无法控制的静脉曲张出血是在急诊情况下需要进行TIPSS的主要指征。近年来,TIPSS在多种疾病中的作用已被重新定义,如异位静脉曲张、门静脉血栓形成、布加综合征、肝静脉闭塞病等。本综述旨在深入分析在急诊情况下何时以及为何应进行TIPSS手术,指出相关的最常见技术难点和并发症。