Herbei Elena Emanuela, Alexandru Petrică, Busila Mariana
Interdisciplinary Research Centre in the Field of Eco-Nano Technology and Advance Materials CC-ITI, Faculty of Engineering, "Dunărea de Jos" University of Galati, 47 Domnească, 800008 Galati, Romania.
Materials (Basel). 2023 Apr 21;16(8):3266. doi: 10.3390/ma16083266.
In this paper, the authors describe the fabrication of nanocomposite chitosan-based systems of zinc oxide (ZnO), silver (Ag) and Ag-ZnO. Recently, the development of coated screen-printed electrodes using metal and metal oxide nanoparticles (NPs) for the specific detection and monitoring of different cancer tumors has been obtaining important results. Ag, ZnO NPs and Ag-ZnO prepared by the hydrolysis of zinc acetate blended with a chitosan (CS) matrix were used for the surface modification of screen-printed carbon electrodes (SPCEs) in order to analyze the electrochemical behavior of the typical redox system of a 10 mM potassium ferrocyanide-0.1 M buffer solution (BS). The solutions of CS, ZnO/CS, Ag/CS and Ag-ZnO/CS were prepared in order to modify the carbon electrode surface, and were measured at different scan rates from 0.02 V/s to 0.7 V/s by cyclic voltammetry. The cyclic voltammetry (CV) was performed on a house-built potentiostat (HBP). The cyclic voltammetry of the measured electrodes showed the influence of varying the scan rate. The variation of the scan rate has an influence on the intensity of the anodic and cathodic peak. Both values of currents (anodic and cathodic currents) have higher values for 0.1 V/s (Ia = 22 μA and Ic = -25 μA) compared to the values for 0.06 V/s (Ia = 10 μA and Ic = -14 μA). The CS, ZnO/CS, Ag/CS and Ag-ZnO/CS solutions were characterized using a field emission scanning electron microscopy (FE-SEM) with EDX elemental analysis. The modified coated surfaces of screen-printed electrodes were analyzed using optical microscopy (OM). The present coated carbon electrodes showed a different waveform compared to the voltage applied to the working electrode, depending on the scan rate and chemical composition of the modified electrodes.
在本文中，作者描述了基于纳米复合壳聚糖的氧化锌（ZnO）、银（Ag）和Ag-ZnO体系的制备。最近，使用金属和金属氧化物纳米颗粒（NPs）制备涂层丝网印刷电极用于不同癌症肿瘤的特异性检测和监测已取得重要成果。通过醋酸锌水解制备的Ag、ZnO NPs和Ag-ZnO与壳聚糖（CS）基质混合，用于丝网印刷碳电极（SPCEs）的表面修饰，以分析10 mM亚铁氰化钾-0.1 M缓冲溶液（BS）典型氧化还原体系的电化学行为。制备了CS、ZnO/CS、Ag/CS和Ag-ZnO/CS溶液以修饰碳电极表面，并通过循环伏安法在0.02 V/s至0.7 V/s的不同扫描速率下进行测量。循环伏安法（CV）在自制恒电位仪（HBP）上进行。测量电极的循环伏安法显示了扫描速率变化的影响。扫描速率的变化对阳极和阴极峰的强度有影响。与0.06 V/s（Ia = 10 μA，Ic = -14 μA）的值相比，0.1 V/s时的两种电流值（阳极电流和阴极电流）更高（Ia = 22 μA，Ic = -25 μA）。使用带有能谱元素分析的场发射扫描电子显微镜（FE-SEM）对CS、ZnO/CS、Ag/CS和Ag-ZnO/CS溶液进行了表征。使用光学显微镜（OM）对丝网印刷电极的修饰涂层表面进行了分析。根据扫描速率和修饰电极的化学成分，当前的涂层碳电极与施加到工作电极的电压相比显示出不同的波形。
