Komaki Hisayuki
Biological Resource Center, National Institute of Technology and Evaluation (NBRC), Chiba 292-0818, Japan.
Microorganisms. 2023 Mar 24;11(4):831. doi: 10.3390/microorganisms11040831.
The genus is a representative group of actinomycetes and one of the largest taxa in bacteria, including approximately 700 species with validly published names. Since the classification was mainly based on phenotypic characteristics in old days, many members needed to be reclassified according to recent molecular-based taxonomies. Recent developments of molecular-based analysis methods and availability of whole genome sequences of type strains enables researchers to reclassify these phylogenetically complex members on a large scale. This review introduces reclassifications of the genus reported in the past decade. Appropriately 34 species were transferred to the other genera, such as , , and recently proposed new genera. As a result of reclassifications of 14 subspecies, the genus includes only four subspecies at present in practice. A total of 63 species were reclassified as later heterotypic synonyms of previously recognized species in 24 published reports. As strong relationships between species and the secondary metabolite-biosynthetic gene clusters become clarified, appropriate classifications of this genus will not only contribute to systematics, but also provide significant information when searching for useful bioactive substances.
该属是放线菌的一个代表性类群，也是细菌中最大的分类单元之一，包括约700个有效发表名称的物种。由于过去的分类主要基于表型特征，许多成员需要根据最近基于分子的分类法重新分类。基于分子的分析方法的最新发展以及模式菌株全基因组序列的可用性，使研究人员能够大规模地对这些系统发育复杂的成员进行重新分类。本综述介绍了过去十年中报道的该属的重新分类情况。约34个物种被转移到其他属，如、、以及最近提出的新属。由于对14个亚种进行了重新分类，该属目前在实际应用中仅包括四个亚种。在24篇已发表的报告中，共有63个物种被重新分类为先前认可物种的后选异名。随着物种与次生代谢物生物合成基因簇之间的紧密关系变得清晰，该属的适当分类不仅将有助于系统分类学，而且在寻找有用的生物活性物质时也将提供重要信息。
