Research Center for Chromatography and Mass Spectrometry (CROM-MASS), Center for Biomolecules (CIBIMOL), Universidad Industrial de Santander, Carrera 27, Calle 9, Bucaramanga 680002, Colombia.
Research Group on Orchids and Ecology, Universidad Nacional de Colombia, Carrera 32, Palmira 763533, Colombia.
Molecules. 2023 Apr 14;28(8):3474. doi: 10.3390/molecules28083474.
Plants of the genus (Lamiaceae) have a wide variety of bioactive secondary metabolites with diverse biological properties, e.g., anti-inflammatory, antiallergenic, antioxidant, antiviral, and antitumor activities. The chemical composition of the hydroethanolic extracts, obtained from dried plants of . , . , and . × . , was determined by UHPLC/ESI-Q-Orbitrap-MS. The flavones were found in a higher proportion. Baicalin and dihydrobaicalein-glucuronide were the major extract components in . (287.127 ± 0.005 mg/g and 140.18 ± 0.07 mg/g), in . (158.3 ± 0.34 mg/g and 51.20 ± 0.02 mg/g), and in . × . (186.87 ± 0.01 mg/g and 44.89 ± 0.06 mg/g). The . extract showed the highest antioxidant activity in the four complementary techniques employed to evaluate all extracts: ORAC (3828 ± 3.0 µmol Trolox/g extract), ABTS (747 ± 1.8 µmol Trolox/g extract), online HPLC-ABTS (910 ± 1.3 µmol Trolox/g extract), and β-carotene (74.3 ± 0.8 µmol Trolox/g extract).
（唇形科）属的植物具有广泛的生物活性次生代谢产物，具有多种生物学特性，例如抗炎、抗变态反应、抗氧化、抗病毒和抗肿瘤活性。通过 UHPLC/ESI-Q-Orbitrap-MS 测定了从干燥的. 、. 、. 和. ×. 植物的水乙醇提取物的化学组成。发现类黄酮的比例更高。黄芩苷和二氢黄芩素-葡萄糖醛酸苷是. （287.127 ± 0.005 mg/g 和 140.18 ± 0.07 mg/g）、. （158.3 ± 0.34 mg/g 和 51.20 ± 0.02 mg/g）和. ×. （186.87 ± 0.01 mg/g 和 44.89 ± 0.06 mg/g）的主要提取物成分。. 提取物在用于评估所有提取物的四种互补技术中的抗氧化活性最高：ORAC（3828 ± 3.0 µmol Trolox/g 提取物）、ABTS（747 ± 1.8 µmol Trolox/g 提取物）、在线 HPLC-ABTS（910 ± 1.3 µmol Trolox/g 提取物）和β-胡萝卜素（74.3 ± 0.8 µmol Trolox/g 提取物）。
