School of Health Sciences, University of Newcastle, Callaghan, NSW 2308, Australia.
School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, NSW 2308, Australia.
Nutrients. 2023 Apr 18;15(8):1943. doi: 10.3390/nu15081943.
Higher dietary intakes of Omega-3 long-chain polyunsaturated fatty acids (-3 LC-PUFAs) have been linked to lower rates of preterm birth and preeclampsia. The aim of this analysis was to describe dietary intake and fractions of red blood cell (RBC) membrane LC-PUFAs during pregnancy in a cohort of Indigenous Australian women. Maternal dietary intake was assessed using two validated dietary assessment tools and quantified using the AUSNUT (Australian Food and Nutrient) 2011-2013 database. Analysis from a 3-month food frequency questionnaire indicated that 83% of this cohort met national -3 LC-PUFA recommendations, with 59% meeting alpha-linolenic acid (ALA) recommendations. No nutritional supplements used by the women contained -3 LC-PUFAs. Over 90% of women had no detectable level of ALA in their RBC membranes, and the median Omega-3 Index was 5.5%. This analysis appears to illustrate a decline in concentrations of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) across gestation in women who had preterm birth. However, there was no visible trend in LC-PUFA fractions in women who experienced hypertension during pregnancy. Further research is needed to better understand the link between dietary intake of -3 LC-PUFA-rich foods and the role of fatty acids in preterm birth and preeclampsia.
较高的ω-3 长链多不饱和脂肪酸（ω-3 LC-PUFA）的饮食摄入量与较低的早产和子痫前期的发生率有关。本分析的目的是描述澳大利亚原住民妇女队列在怀孕期间的饮食摄入量和红细胞（RBC）膜 LC-PUFA 分数。使用两种经过验证的饮食评估工具评估母体饮食摄入量，并使用 AUSNUT（澳大利亚食物和营养）2011-2013 数据库进行量化。来自 3 个月的食物频率问卷的分析表明，该队列中有 83%的人符合国家ω-3 LC-PUFA 建议，其中 59%的人符合α-亚麻酸（ALA）建议。妇女使用的任何营养补充剂均不含ω-3 LC-PUFA。超过 90%的女性 RBC 膜中检测不到 ALA，ω-3 指数中位数为 5.5%。该分析似乎表明，在早产的妇女中，随着妊娠的进展，二十碳五烯酸（EPA）和二十二碳六烯酸（DHA）的浓度下降。然而，在怀孕期间患有高血压的妇女中，LC-PUFA 分数没有明显的趋势。需要进一步研究，以更好地了解富含ω-3 LC-PUFA 的食物的饮食摄入量与脂肪酸在早产和子痫前期中的作用之间的联系。
