Palka J, Malone M A, Ellison R L, Wigston D J
J Neurosci. 1986 Jun;6(6):1822-30. doi: 10.1523/JNEUROSCI.06-06-01822.1986.
Eight sensory structures (campaniform sensilla), appearing identical in the light and scanning electron microscopes, are found in specific locations on the wings of Drosophila. Their axons enter one of 2 central tracts, a medial one or a lateral one. The topographic arrangement of the sensilla on the wing is not reflected in this central projection pattern. There is, however, a strict correlation between the time when a sensillum develops and the path its axon follows: The 4 sensilla whose axons form the medial projection are born and differentiate early during the development of the wing, while the other 4 sensilla, all of which project laterally, arise during a second wave of differentiation. This time-related projection pattern remains stable in the face of a variety of genetically induced alterations in the precise number and location of sensilla.
在果蝇翅膀的特定位置发现了八个感觉结构(钟形感器),在光学显微镜和扫描电子显微镜下看起来相同。它们的轴突进入两条中央神经束之一,即内侧神经束或外侧神经束。翅膀上感器的拓扑排列在这种中央投射模式中并未体现出来。然而,感器发育的时间与其轴突所走的路径之间存在严格的相关性:轴突形成内侧投射的四个感器在翅膀发育早期产生并分化,而另外四个全部向外侧投射的感器则在第二轮分化过程中出现。面对各种由基因诱导的感器精确数量和位置的改变,这种与时间相关的投射模式保持稳定。