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帕金森病与口腔健康:系统综述。

Parkinson's disease and oral health: A systematic review.

机构信息

Department of Orofacial Pain and Dysfunction, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.

Department of Orofacial Pain and Dysfunction, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.

出版信息

Arch Oral Biol. 2023 Jul;151:105712. doi: 10.1016/j.archoralbio.2023.105712. Epub 2023 Apr 25.

DOI:10.1016/j.archoralbio.2023.105712
PMID:37120970
Abstract

OBJECTIVE

in patients with Parkinson's Disease (PD), oral health can be affected by motor and non-motor symptoms and/or medication use. Therefore, the aim was to systematically review the literature on oral health and associated factors of oral health in PD patients.

DESIGN

a literature search was performed from inception up to April 5th, 2023. Original studies that assessed oral health-related factors in PD patients and were written in English or Dutch, were included.

RESULTS

11276 articles were identified, of which 43 met the inclusion criteria (quality range poor-good). A higher prevalence of dental biofilm, bleeding/gingivitis, pocket depth (≥4 mm), tooth mobility, caries, and number of decayed missing filled teeth/surfaces was found in PD patients than in controls. However, no difference between both groups was found when analysing edentulism and wearing dentures. Poor oral health of PD patients was associated with a longer disease duration, higher disease severity, and more prescribed medications.

CONCLUSIONS

oral health of PD patients is worse than that of healthy individuals. It is associated with the duration and severity of PD and medication use. Therefore, we advise regular appointments with oral health care professionals, with an important focus on prevention.

摘要

目的

帕金森病(PD)患者的口腔健康可能受到运动和非运动症状以及/或药物使用的影响。因此,本研究旨在系统回顾 PD 患者口腔健康及相关因素的文献。

设计

从建库至 2023 年 4 月 5 日进行文献检索。纳入评估 PD 患者口腔健康相关因素且使用英语或荷兰语书写的原始研究。

结果

共确定了 11276 篇文章,其中 43 篇符合纳入标准(质量范围为差-好)。与对照组相比,PD 患者的牙菌斑、牙龈出血/炎、牙周袋深度(≥4mm)、牙齿松动、龋齿和龋齿/缺失/补牙数/面数的发生率更高。然而,在分析无牙和戴义齿方面,两组之间没有差异。PD 患者口腔健康状况较差与疾病持续时间较长、疾病严重程度较高以及服用的药物较多有关。

结论

PD 患者的口腔健康状况差于健康个体。它与 PD 的持续时间和严重程度以及药物使用有关。因此,我们建议定期与口腔保健专业人员预约,重点关注预防。

相似文献

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Parkinson's disease and oral health: A systematic review.帕金森病与口腔健康:系统综述。
Arch Oral Biol. 2023 Jul;151:105712. doi: 10.1016/j.archoralbio.2023.105712. Epub 2023 Apr 25.
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