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浆液性癌来源的去分化子宫内膜癌:诊断挑战与建议

Dedifferentiated endometrial carcinoma arising from serous carcinoma: Diagnostic challenges and recommendations.

作者信息

Xu Zhengfan, Saikia Kasturi, Yuan Lisi

机构信息

Department of Pathology and Laboratory Medicine, Henry Ford Health System, Detroit, MI, USA.

出版信息

Gynecol Oncol Rep. 2023 Apr 13;47:101188. doi: 10.1016/j.gore.2023.101188. eCollection 2023 Jun.

DOI:10.1016/j.gore.2023.101188
PMID:37122437
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10130470/
Abstract

•Dedifferentiated endometrial carcinoma arising from serous carcinoma (null-type P53).•Differential diagnosis including carcinosarcoma, FIGO grade 3 endometrioid carcinoma.•Also need to rule out SMARCA4-deficient uterine sarcoma and other sarcomas.

摘要

•由浆液性癌(P53 缺失型)引起的去分化子宫内膜癌。

•鉴别诊断包括癌肉瘤、国际妇产科联盟(FIGO)3 级子宫内膜样癌。

•还需要排除 SMARCA4 缺陷型子宫肉瘤和其他肉瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48a3/10130470/dc26326a41f2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48a3/10130470/be558c61d476/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48a3/10130470/dc26326a41f2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48a3/10130470/be558c61d476/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48a3/10130470/dc26326a41f2/gr2.jpg

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Semin Diagn Pathol. 2022 May;39(3):176-186. doi: 10.1053/j.semdp.2021.11.002. Epub 2021 Nov 20.
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Clinico-pathological significance of TCGA classification and SWI/SNF proteins expression in undifferentiated/dedifferentiated endometrial carcinoma: A possible prognostic risk stratification.
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Gynecol Oncol. 2021 May;161(2):629-635. doi: 10.1016/j.ygyno.2021.02.029. Epub 2021 Mar 10.
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Gynecol Oncol. 2021 Apr;161(1):113-121. doi: 10.1016/j.ygyno.2021.01.025. Epub 2021 Feb 2.
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ESGO/ESTRO/ESP guidelines for the management of patients with endometrial carcinoma.ESGO/ESTRO/ESP 子宫内膜癌管理指南。
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