Levin Scott R, Burke Peter A, Brahmbhatt Tejal S, Siracuse Jeffrey J, Slama Jaromir, Roh Daniel S
Division of Plastic and Reconstructive Surgery, Boston Medical Center, Boston University School of Medicine, Boston, Mass.
Division of Trauma, Acute Care Surgery, and Surgical Critical Care, Boston Medical Center, Boston University School of Medicine, Boston, Mass.
Plast Reconstr Surg Glob Open. 2023 Apr 26;11(4):e4961. doi: 10.1097/GOX.0000000000004961. eCollection 2023 Apr.
Identifying risk factors for traumatic lower extremity reconstruction outcomes has been limited by sample size. We evaluated patient and procedural characteristics associated with reconstruction outcomes using data from almost four million patients.
The National Trauma Data Bank (2015-2018) was queried for lower extremity reconstructions. Univariable and multivariable analyses determined associations with inpatient outcomes.
There were 4675 patients with lower extremity reconstructions: local flaps (77%), free flaps (19.2%), or both (3.8%). Flaps were most commonly local fasciocutaneous (55.1%). Major injuries in reconstructed extremities were fractures (56.2%), vascular injuries (11.8%), and mangled limbs (2.9%). Ipsilateral procedures prereconstruction included vascular interventions (6%), amputations (5.6%), and fasciotomies (4.3%). Postoperative surgical site infection and amputation occurred in 2% and 2.6%, respectively. Among survivors (99%), mean total length of stay (LOS) was 23.2 ± 21.1 days and 46.8% were discharged to rehab. On multivariable analysis, vascular interventions prereconstruction were associated with increased infection [odds ratio (OR) 1.99, 95% confidence interval (CI) 1.05-3.79, = 0.04], amputation (OR 4.38, 95% CI 2.56-7.47, < 0.001), prolonged LOS (OR 1.59, 95% CI 1.14-2.22, = 0.01), and discharge to rehab (OR 1.49, 95% CI 1.07-2.07, = 0.02). Free flaps were associated with prolonged LOS (OR 2.08, 95% CI 1.74-2.49, < 0.001).
Prereconstruction vascular interventions were associated with higher incidences of adverse outcomes. Free flaps correlated with longer LOS, but otherwise similar outcomes. Investigating reasons for increased complication and healthcare utilization likelihood among these subgroups is warranted.
由于样本量的限制,确定创伤性下肢重建结果的危险因素一直受到制约。我们使用近四百万患者的数据评估了与重建结果相关的患者和手术特征。
查询国家创伤数据库(2015 - 2018年)中下肢重建的数据。单变量和多变量分析确定了与住院结果的关联。
有4675例患者进行了下肢重建:局部皮瓣(77%)、游离皮瓣(19.2%)或两者皆用(3.8%)。皮瓣最常见的是局部筋膜皮瓣(55.1%)。重建肢体的主要损伤为骨折(56.2%)、血管损伤(11.8%)和肢体毁损(2.9%)。重建前同侧的手术包括血管介入(6%)、截肢(5.6%)和筋膜切开术(4.3%)。术后手术部位感染和截肢发生率分别为2%和2.6%。在幸存者(99%)中,平均总住院时间(LOS)为23.2±21.1天,46.8%的患者出院后前往康复机构。多变量分析显示,重建前的血管介入与感染增加相关[比值比(OR)1.99,95%置信区间(CI)1.05 - 3.79,P = 0.04]、截肢(OR 4.38,95% CI 2.56 - 7.47,P < 0.001)、住院时间延长(OR 1.59,95% CI 1.14 - 2.22,P = 0.01)以及出院后前往康复机构(OR 1.49,95% CI 1.07 - 2.07,P = 0.02)。游离皮瓣与住院时间延长相关(OR 2.08,95% CI 1.74 - 2.49,P < 0.001)。
重建前的血管介入与不良结果的较高发生率相关。游离皮瓣与较长的住院时间相关,但其他结果相似。有必要研究这些亚组中并发症增加和医疗资源利用可能性增加的原因。