Department of Surgical Oncology, Mercer University School of Medicine, Macon, GA, USA.
Department of Surgery, Mercer University School of Medicine, Macon, GA, USA.
Am Surg. 2023 Aug;89(8):3650-3651. doi: 10.1177/00031348231173961. Epub 2023 May 2.
Eccrine porocarcinoma is a rare and aggressive cutaneous malignancy that develops in the seventh and eight decades of life. We present a 76-year-old male with eccrine porocarcinoma developing from a long standing previously benign lesion who underwent successful treatment with wide local excision. It can also develop de novo, presenting most commonly as a mass or nodule. Tissue biopsy with histopathology is required to confirm the diagnosis. Wide local excision is recommended for local disease. Radiation and chemotherapy can be used as adjuncts in advanced and metastatic disease. Given its rarity, there are no guidelines to direct therapy for locally advance or metastatic disease and for follow-up. Further studies are needed to better understand and guide management of this entity.
大汗腺癌是一种罕见且侵袭性的皮肤恶性肿瘤，发生于七、八十岁。我们报告一位 76 岁男性，其大汗腺癌源自长期存在的先前良性病变，经广泛局部切除后成功治疗。它也可以从头发生，最常见的表现为肿块或结节。组织活检和组织病理学检查是确诊所必需的。广泛局部切除适用于局部疾病。对于晚期和转移性疾病，可以使用放疗和化疗作为辅助治疗。鉴于其罕见性，对于局部进展或转移性疾病以及随访，尚无指导治疗的指南。需要进一步的研究来更好地了解和指导这种疾病的管理。
