Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN; Department of Medicine, Hennepin Healthcare, University of Minnesota, Minneapolis, MN.
Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN.
Am J Transplant. 2023 Feb;23(2 Suppl 1):S475-S522. doi: 10.1016/j.ajt.2023.02.011.
This chapter updates the COVID-19 chapter from the 2020 Annual Data Report with trends through February 12, 2022, and introduces trends in COVID-19-specific cause of death on the waiting list and posttransplant. Transplant rates remain at or above prepandemic levels for all organs, indicating a sustained transplantation system recovery following the initial 3-month disruption due to the onset of the pandemic. Posttransplant mortality and graft failure remain a concern in all organs, with rates surging corresponding to waves of the pandemic. Waitlist mortality due to COVID-19 is also a concern, particularly among kidney candidates. While the recovery of the transplantation system has been sustained in the second year of the pandemic, ongoing efforts should focus on reducing posttransplant and waitlist mortality due to COVID-19, and graft failure.
这一章用截至 2022 年 2 月 12 日的趋势更新了 2020 年年度数据报告中的 COVID-19 章节,并介绍了等待名单和移植后 COVID-19 特定死因的趋势。所有器官的移植率仍保持在或高于大流行前的水平,表明在最初因大流行而中断的 3 个月后,移植系统持续恢复。所有器官的移植后死亡率和移植物失功仍然令人担忧,其发生率与大流行的浪潮相对应。由于 COVID-19 导致的等待名单死亡率也是一个关注点,尤其是在肾脏候选者中。虽然在大流行的第二年,移植系统的恢复一直在持续,但持续的努力应侧重于降低 COVID-19 导致的移植后和等待名单死亡率以及移植物失功。