Section of Nephrology and Selzman Institute for Kidney Health, Baylor College of Medicine, Houston, TX, USA.
Division of Nephrology and Solid-Organ Transplantation, Michael E. DeBakey VA Medical Center, Houston, TX, USA.
Transpl Int. 2021 Apr;34(4):612-621. doi: 10.1111/tri.13840. Epub 2021 Feb 26.
The COVID-19 pandemic has significantly changed the landscape of kidney transplantation in the United States and worldwide. In addition to adversely impacting allograft and patient survival in postkidney transplant recipients, the current pandemic has affected all aspects of transplant care, including transplant referrals and listing, organ donation rates, organ procurement and shipping, and waitlist mortality. Critical decisions were made during this period by transplant centers and individual transplant physicians taking into consideration patient safety and resource utilization. As countries have begun administering the COVID vaccines, new and important considerations pertinent to our transplant population have arisen. This comprehensive review focuses on the impact of COVID-19 on kidney transplantation rates, mortality, policy decisions, and the clinical management of transplanted patients infected with COVID-19.
新冠疫情大流行极大地改变了美国和全球范围内的肾脏移植格局。除了对肾移植受者的移植物和患者生存率产生不利影响外,当前的大流行还影响了移植护理的各个方面,包括移植推荐和登记、器官捐赠率、器官获取和运输以及候补名单死亡率。移植中心和个别移植医生在此期间做出了关键决策,考虑到了患者安全和资源利用。随着各国开始接种 COVID 疫苗,我们的移植人群出现了新的和重要的相关问题。本综述全面探讨了 COVID-19 对肾脏移植率、死亡率、政策决策以及感染 COVID-19 的移植患者的临床管理的影响。