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基于腰椎 L2-L4 骨密度 T 评分的绝经后妇女骨质疏松症和低骨量的危险因素:伊朗的一项研究。

Risk factors of osteoporosis and osteopenia in postmenopausal women based on the L2-L4 BMD T score of the lumbar spine: a study in Iran.

机构信息

Iran University of Medical Sciences, Akbarabadi Teaching Hospital, Akbarabadi Clinical Research Development Unit, Tehran, Iran.

Fellowship of Minimally Invasive Gynecology, Zanjan University of Medical Sciences, Zanjan, Iran.

出版信息

Gynecol Endocrinol. 2023 Apr 27;39(1):2205959. doi: 10.1080/09513590.2023.2205959.

Abstract

OBJECTIVE

To determine the risk factors of osteoporosis and osteopenia of the spine in postmenopausal women.

METHOD

An analytical cross-sectional study was performed on postmenopausal women. The T-score of the lumbar spine (L2-L4) was measured by densitometry and compared between osteoporotic, osteopenia, and normal women.

RESULTS

postmenopausal women were evaluated. The prevalence of osteopenia and osteoporosis was 58.2% and 12.8% respectively. Age, BMI, parity, total breastfeeding years, dairy use, calcium-D supplements, and regular exercise were significantly different in women with osteoporosis, osteopenia, and normal women. Ethnicity, diabetes, and previous fracture history were only other among women with osteoporosis (not osteopenia) and normal women. For osteopenia of the spine, age [AOR 1.08 (1.05-1.11;  < .001)] was the risk factor, and BMI = >30 [AOR 0.36 (0.28-0.58;  < .001)] and BMI 25-<30 [AOR 0.55 (0.34-0.88;  = .012)] were protective factors. Hyperthyroidism (AOR 23.43,  = .010), Kurdish ethnicity (AOR 2.96,  = .009), not having regular exercise (AOR 2.22,  = .012), previous fracture history (AOR 2.15,  = .041)], and age (AOR 1.14,  < .001)], were risk factors for osteoporosis, while BMI ≥30 [AOR 0.09,  < .001], BMI 25-<30 [AOR 0.28,  = .001], and diabetes [AOR 0.41,  = .038] were protective factors for osteoporosis of the spine.

CONCLUSION

Hyperthyroidism, low BMI <25, parity ≥ 6, Kurdish ethnicity, not having regular exercise, history of previous fracture, and age, were risk factors for osteoporosis of the spine respectively, while low BMI and age were risk factors for osteopenia.

摘要

目的

确定绝经后妇女脊柱骨质疏松和骨量减少的危险因素。

方法

对绝经后妇女进行分析性横断面研究。通过密度测定法测量腰椎(L2-L4)的 T 评分,并比较骨质疏松、骨量减少和正常妇女之间的 T 评分。

结果

评估了绝经后妇女。骨质疏松和骨量减少的患病率分别为 12.8%和 58.2%。年龄、BMI、产次、总母乳喂养年限、乳制品使用、钙-D 补充剂和规律运动在骨质疏松、骨量减少和正常妇女中差异显著。种族、糖尿病和既往骨折史仅在骨质疏松(而非骨量减少)和正常妇女中存在差异。对于脊柱骨量减少,年龄[OR 1.08(1.05-1.11; < .001)]是危险因素,而 BMI = >30[OR 0.36(0.28-0.58; < .001)]和 BMI 25-<30[OR 0.55(0.34-0.88; = .012)]是保护因素。甲状腺功能亢进症(OR 23.43, = .010)、库尔德族裔(OR 2.96, = .009)、无规律运动(OR 2.22, = .012)、既往骨折史(OR 2.15, = .041)]和年龄(OR 1.14, < .001)]是骨质疏松的危险因素,而 BMI ≥30[OR 0.09, < .001]、BMI 25-<30[OR 0.28, = .001]和糖尿病[OR 0.41, = .038]是骨质疏松的保护因素。

结论

甲状腺功能亢进症、低 BMI<25、产次≥6、库尔德族裔、无规律运动、既往骨折史和年龄分别是骨质疏松的危险因素,而低 BMI 和年龄是骨量减少的危险因素。

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