J Opt Soc Am A Opt Image Sci Vis. 2023 Apr 1;40(4):714-721. doi: 10.1364/JOSAA.483300.
Mueller matrix polarization imaging is a new biomedical optical imaging method that can generate both polarization and isotropic intensity images of structures of the biological tissue sample surface. In this paper, a Mueller polarization imaging system in the reflection mode is described for obtaining the Mueller matrix of the specimens. Diattenuation, phase retardation, and depolarization of the specimens are derived by using the conventional Mueller matrix polarization decomposition method and a newly proposed direct method. The results show that the direct method is more convenient and faster than the conventional decomposition method. The polarization parameter combination method is then presented in which any two of the diattenuation, phase retardation, and depolarization parameters are combined, and three new quantitative parameters are defined in order to reveal more detailed anisotropic structures. The images of in vitro samples are presented to demonstrate the capability of the parameters introduced.
穆勒矩阵偏振成像技术是一种新兴的生物医学光学成像方法，可以生成生物组织样品表面结构的偏振和各向同性强度图像。本文描述了一种用于获取样品穆勒矩阵的反射模式下的穆勒偏振成像系统。通过使用传统的穆勒矩阵偏振分解方法和新提出的直接方法，推导出了样品的消光、相位延迟和去偏振。结果表明，直接方法比传统的分解方法更方便、更快。然后提出了偏振参数组合方法，其中将消光、相位延迟和去偏振参数中的任意两个组合，并定义了三个新的定量参数，以便揭示更详细的各向异性结构。给出了体外样本的图像，以验证所引入参数的性能。
