Lecturer of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
IVF Consultant, Albaraka Fertility Hospital, Manama, Bahrain.
JBRA Assist Reprod. 2023 Sep 12;27(3):367-372. doi: 10.5935/1518-0557.20220063.
Due to the large increase in the number of reported cases and the impact of COVID-19 on public health, the European Society for Human Reproduction and Embryology (ESHRE) recommended the cessation of all activities related to assisted reproduction. There are many unknowns about the long-term effects of the virus on fertility and pregnancy. We conducted this study to offer some evidence-based guidance on the relationship between COVID-19 and IVF/ICSI cycle outcomes.
This observational study included 179 patients who underwent ICSI cycles at the Albaraka Fertility Hospital, Manama, Bahrain and the Almana hospital, KSA. The patients were divided into two groups. Group 1 included 88 individuals with a history of Covid-19 and Group 2 included 91 subjects without a history of COVID-19.
Despite the higher pregnancy (45.1% vs. 36.4%, with p=0.264) and fertilization (52% vs. 50.6% with p=0.647) rates seen in patients without a history of COVID-19, the differences were not statistically significant.
There is no clear evidence that exposure to COVID-19 significantly affects ICSI cycle outcomes.
由于报告病例数量的大量增加以及 COVID-19 对公共卫生的影响,欧洲人类生殖与胚胎学会(ESHRE)建议停止所有与辅助生殖相关的活动。关于该病毒对生育和妊娠的长期影响,有许多未知因素。我们进行这项研究,旨在为 COVID-19 与 IVF/ICSI 周期结局之间的关系提供一些循证指导。
这项观察性研究纳入了在巴林麦纳麦的 Albaraka 生育医院和沙特阿拉伯的 Almana 医院接受 ICSI 周期治疗的 179 名患者。患者被分为两组。第 1 组包括 88 名有 COVID-19 病史的个体,第 2 组包括 91 名无 COVID-19 病史的个体。
尽管无 COVID-19 病史的患者的妊娠率(45.1%比 36.4%,p=0.264)和受精率(52%比 50.6%,p=0.647)较高,但差异无统计学意义。
目前尚无明确证据表明接触 COVID-19 会显著影响 ICSI 周期结局。