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中国成年精神分裂症患者的自杀意念:与神经认知功能和共情的关系。

Suicidal ideation in Chinese adults with schizophrenia: associations with neurocognitive function and empathy.

机构信息

School of Mental Health, Wenzhou Medical University, Wenzhou, Zhejiang, China.

Lishui Second People's Hospital Affiliated to Wenzhou Medical University, Lishui, China.

出版信息

BMC Psychiatry. 2023 May 3;23(1):311. doi: 10.1186/s12888-023-04739-3.

Abstract

BACKGROUND

Suicidal ideation is common among people diagnosed with schizophrenia spectrum disorders and may be related to neurocognitive, social cognitive, and clinical variables. This study aimed to investigate the relationships between suicidal ideation and both neurocognitive function and empathy.

METHODS

The sample for this cross-sectional study comprised 301 schizophrenic patients aged 18-44 years. All participants were administered the Beck Scale for Suicide Ideation-Chinese Version (BSI-CV), the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), the Interpersonal Reactivity Index (IRI), and the Positive and Negative Syndrome Scale (PANSS). The demographic and clinical data of the patients were also collected.

RESULTS

In total, 82 patients reported suicidal ideation. Compared to patients without suicidal ideation, patients with suicidal ideation showed significant differences in the IRI-Personal Distress subscale, PANSS-General Psychopathology symptom scores, and suicide attempts. Moreover, there were moderating effects of neurocognitive function and empathy on the relationship between suicide attempts and suicidal ideation.

CONCLUSIONS

These results indicate that the personal distress component of empathy, general psychopathology symptoms and suicide attempts are independent risk factors for suicidal ideation in Chinese adults with schizophrenia. Moreover, neurocognitive function may also be related to suicidal ideation through a moderating relationship. In order to reduce suicidal ideation among patients with schizophrenia, early screening of empathy and neurocognitive function is essential.

摘要

背景

自杀意念在被诊断为精神分裂症谱系障碍的人群中很常见,可能与神经认知、社会认知和临床变量有关。本研究旨在探讨自杀意念与神经认知功能和同理心之间的关系。

方法

本横断面研究的样本包括 301 名年龄在 18-44 岁的精神分裂症患者。所有参与者均接受贝克自杀意念量表中文版(BSI-CV)、重复认知评估系统(RBANS)、人际反应指数(IRI)和阳性和阴性症状量表(PANSS)的评估。还收集了患者的人口统计学和临床数据。

结果

共有 82 名患者报告有自杀意念。与无自杀意念的患者相比,有自杀意念的患者在 IRI-个人痛苦分量表、PANSS-一般精神病症状评分和自杀尝试方面存在显著差异。此外,神经认知功能和同理心对自杀尝试和自杀意念之间的关系存在调节作用。

结论

这些结果表明,同理心的个人痛苦成分、一般精神病症状和自杀尝试是中国成年精神分裂症患者自杀意念的独立风险因素。此外,神经认知功能也可能通过调节关系与自杀意念有关。为了降低精神分裂症患者的自杀意念,早期筛查同理心和神经认知功能至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11b6/10155378/77d106969056/12888_2023_4739_Fig1_HTML.jpg

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