Punjani Nahid, Andrusier Miriam, Hayden Russell, Dudley Vanessa, Matos-Vargas Eliana, Goldstein Marc
Center for Male Reproductive Medicine and Surgery, Weill Cornell Medical College, New York, New York.
State University of New York Downstate Medical Center College of Medicine, New York, New York.
Urol Pract. 2021 May;8(3):337-340. doi: 10.1097/UPJ.0000000000000218. Epub 2021 Feb 4.
Vasectomy is the most effective form of permanent male contraception. Although vasectomy techniques and outcomes have steadily improved, postvasectomy semen analysis compliance remains a significant challenge. The aim of this study was to assess if home testing improved postvasectomy semen analysis compliance.
Data were collected prospectively but retrospectively reviewed between 2007 and 2019 from a single surgeon's high volume practice. Subjects were divided into 2 groups based on postvasectomy semen analysis method (home vs office) and further subdivided by compliance status. Patients were considered compliant if they provided at least 1 semen sample postvasectomy. Statistical analysis was completed to determine factors predictive of compliance.
A total of 364 patients were included. Median age for the home group vs the office group was similar (42 years [IQR 39-46] vs 41 years [IQR 38-46]). Median number of children for both groups was 2 (IQR 2-3). In all, 109 men (30.0%) opted for at-home testing. No significant difference in compliance was found (59.6% of home test vs 58.8% of laboratory patients, p=0.89). No statistically significant difference in patient demographics (age, partner age, number of children, smoking and alcohol) was observed, and there were no demographic factors predicting compliance with regression modeling.
At-home semen analysis kits did not significantly improve compliance. Clinicians should be aware that this may be a reasonable alternative for those who are unable to obtain a postvasectomy semen analysis in-office. Contact of the female partner instead may improve postvasectomy semen analysis compliance as the female partner has a stake in ensuring postvasectomy semen analysis azoospermia.
输精管结扎术是男性永久性避孕最有效的方式。尽管输精管结扎术的技术和效果在稳步改善,但输精管结扎术后精液分析的依从性仍然是一项重大挑战。本研究的目的是评估家庭检测是否能提高输精管结扎术后精液分析的依从性。
前瞻性收集2007年至2019年间来自一位高手术量外科医生的临床数据,并进行回顾性分析。根据输精管结扎术后精液分析方法(家庭检测与门诊检测)将受试者分为两组,并进一步按依从性状态细分。如果患者在输精管结扎术后至少提供1份精液样本,则认为其依从。完成统计分析以确定预测依从性的因素。
共纳入364例患者。家庭检测组与门诊检测组的中位年龄相似(分别为42岁[四分位间距39 - 46岁]和41岁[四分位间距38 - 46岁])。两组的子女中位数均为2个(四分位间距2 - 3个)。共有109名男性(30.0%)选择家庭检测。依从性方面未发现显著差异(家庭检测组为59.6%,实验室检测患者组为58.8%,p = 0.89)。在患者人口统计学特征(年龄、伴侣年龄、子女数量、吸烟和饮酒情况)方面未观察到统计学显著差异,回归模型分析也未发现有预测依从性的人口统计学因素。
家庭精液分析试剂盒并未显著提高依从性。临床医生应意识到,对于那些无法在门诊进行输精管结扎术后精液分析的患者,这可能是一种合理的替代方法。相反,与女性伴侣沟通可能会提高输精管结扎术后精液分析的依从性,因为女性伴侣在确保输精管结扎术后精液分析无精子症方面也有利害关系。