Exercise Metabolism and Performance Lab (EMPL), Department of Exercise Physiology, Faculty of Sport Sciences, Razi University, Kermanshah, Iran.
Exercise Metabolism and Performance Lab (EMPL), Department of Exercise Physiology, Faculty of Sport Sciences, Razi University, Kermanshah, Iran.
J Affect Disord. 2023 Aug 1;334:12-20. doi: 10.1016/j.jad.2023.04.108. Epub 2023 May 3.
High prevalence of psychiatric comorbidities associated with migraine increases the risk of evolution from episodic migraine to chronic migraine. This study investigated the effects of eight weeks of aerobic exercise and vitamin D supplementation on psychiatric comorbidities in men with migraine and vitamin D insufficiency.
Forty-eight participants took part in this randomized controlled clinical trial and were allocated into four groups: aerobic exercise and vitamin D (AE + VD), aerobic exercise and placebo (AE + Placebo), vitamin D (VD), and Placebo. AE + VD and AE + Placebo groups performed three aerobic exercise sessions per week for eight weeks and received a vitamin D supplement and placebo, respectively. The VD group received a vitamin D supplement, and the Placebo group received a placebo for eight weeks. The depression severity, quality of sleep, and physical self-concept were measured at baseline and after eight weeks.
The results showed that depression severity was significantly lower in AE + VD compared to AE + Placebo, VD, and Placebo at the post-test. Our results demonstrated that in the post-test, the mean score of sleep quality in AE + VD was significantly lower than AE + Placebo, VD, and Placebo. Finally, the results revealed that after eight weeks of intervention, the physical self-concept in AE + VD was significantly higher than in VD and Placebo groups.
Not having complete control of sun exposure and the diet were the limitations.
The results indicated that the concomitant application of AE and VD supplementation could provoke synergistic effects leading to additional psycho-cognitive health benefits in men with migraine and vitamin D insufficiency.
与偏头痛相关的精神共病患病率较高，增加了从阵发性偏头痛向慢性偏头痛发展的风险。本研究调查了八周有氧运动和维生素 D 补充对偏头痛和维生素 D 不足男性精神共病的影响。
48 名参与者参加了这项随机对照临床试验，并被分为四组：有氧运动和维生素 D（AE + VD）、有氧运动和安慰剂（AE + 安慰剂）、维生素 D（VD）和安慰剂。AE + VD 和 AE + 安慰剂组每周进行三次有氧运动，持续八周，并分别接受维生素 D 补充剂和安慰剂。VD 组接受维生素 D 补充剂，安慰剂组接受安慰剂八周。在基线和八周后测量抑郁严重程度、睡眠质量和身体自我概念。
结果表明，与 AE + 安慰剂、VD 和安慰剂相比，AE + VD 组在 post-test 时抑郁严重程度显著降低。我们的结果表明，在 post-test 时，AE + VD 组的睡眠质量平均得分明显低于 AE + 安慰剂、VD 和安慰剂组。最后，结果显示，干预八周后，AE + VD 组的身体自我概念明显高于 VD 和安慰剂组。
无法完全控制阳光照射和饮食是本研究的局限性。
结果表明，AE 和 VD 补充的同时应用可能会产生协同作用，为偏头痛和维生素 D 不足的男性带来额外的心理认知健康益处。
