Department of Global Health Policy, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Pre-clinical Department, University of Medicine 2, Yangon, Myanmar.
Arch Pediatr. 2023 Aug;30(6):372-377. doi: 10.1016/j.arcped.2023.03.010. Epub 2023 May 4.
Anemia and stunting in children are detrimental to the prospects of a normal, healthy upbringing. Having similar risk factors and serious consequences, the syndemic aspect of these two ailments is mostly underrated, and positive deviant (PD) factors that ensure non-anemic status in stunted children have not been studied to date.
This study aimed to identify PD factors that have potential to prevent syndemic anemia among stunted children aged 6-59 months in Myanmar. This was a cross-sectional secondary analysis of the Myanmar Demographic and Health Survey (DHS) data conducted in 2016, applying the PD concept, where children who were stunted without anemia were considered as PDs.
Among 1248 stunted children, those who had the syndemic condition were compared with their PD peers in terms of maternal characteristics as well as socioeconomic and health-related factors. Multivariable logistic regression analyses were used to identify the determinants of syndemic state. The results showed that three out of every five stunted children were anemic. The syndemic risk was decreased among children of maternal age groups 20-34 years and 35-44 years: [aOR] = 0.19, 95% CI = 0.05-0.69; p = 0.012, and aOR = 0.19, 95% CI = 0.05-0.75; p = 0.018, respectively. Moderately stunted children (aOR = 0.53, 95% CI = 0.34-0.81; p = 0.004) and children who were not currently breastfed (aOR = 1.56, 95% CI = 1.01-2.41; p = 0.044) were less likely to develop the syndemic condition.
Maternal age, stunting severity, breastfeeding duration, and maternal anemic status are strong predictors in determining hemoglobin concentrations among stunted children. This study suggests that nutritional interventions targeting PD factors could represent syndemic action in improving child health.
儿童贫血和发育迟缓不利于其正常、健康成长。这两种疾病具有相似的风险因素和严重后果,但它们的综合征发病方面大多被低估了,而且目前尚未研究能够确保发育迟缓儿童不发生贫血的正向偏离(PD)因素。
本研究旨在确定可能预防缅甸 6-59 月龄发育迟缓儿童综合征性贫血的 PD 因素。这是对 2016 年进行的缅甸人口与健康调查(DHS)数据的横断面二次分析,应用 PD 概念,即不贫血的发育迟缓儿童被视为 PD。
在 1248 名发育迟缓儿童中,将具有综合征状况的儿童与他们的 PD 同龄人进行比较,比较内容包括母亲特征以及社会经济和与健康相关的因素。采用多变量逻辑回归分析来确定综合征状态的决定因素。结果表明,每五个发育迟缓儿童中就有三个患有贫血。在母亲年龄组为 20-34 岁和 35-44 岁的儿童中,综合征风险降低:[比值比(aOR)] = 0.19,95%置信区间(CI)= 0.05-0.69;p = 0.012,和 aOR = 0.19,95% CI = 0.05-0.75;p = 0.018,分别。中度发育迟缓的儿童(aOR = 0.53,95% CI = 0.34-0.81;p = 0.004)和目前未母乳喂养的儿童(aOR = 1.56,95% CI = 1.01-2.41;p = 0.044)不太可能出现综合征状况。
母亲年龄、发育迟缓严重程度、母乳喂养持续时间和母亲贫血状况是决定发育迟缓儿童血红蛋白浓度的重要预测因素。本研究表明,针对 PD 因素的营养干预措施可能代表改善儿童健康的综合征行动。