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印度尼西亚西爪哇省万隆地区6至24个月发育迟缓儿童的贫血状况评估

The Evaluation of Anemia Among Stunted Children Aged 6-24 Months in Bandung District, West Java, Indonesia.

作者信息

Susanah Susi, Marcelius David, Rakhmilla Lulu Eva, Rossanti Rini, Febrianti Sindy Amalia, Sakinah Siti, Winyarti Winyarti, Lutfia Safira Satyani, Judistiani Raden Tina Dewi, Gurnida Dida Akhmad, Setiabudiawan Budi

机构信息

Department of Child Health, Hematology-Oncology Division, Dr. Hasan Sadikin General Hospital/Faculty of Medicine, Universitas Padjadjaran, Bandung 40161, Indonesia.

Department of Child Health, Faculty of Medicine, Universitas Padjadjaran, Bandung 40161, Indonesia.

出版信息

Children (Basel). 2025 May 15;12(5):638. doi: 10.3390/children12050638.

Abstract

: Anemia, particularly iron-deficiency anemia (IDA), and stunting remain notable early childhood public health challenges in Indonesia; however, studies are still scarce. This study aimed to determine the co-occurrence of anemia and stunting (CAS), their prevalence, and the associated factors, as well as to describe the erythrocyte parameters. : Approximately 2200 children aged 6-24 months were identified by midwives to have problematic nutritional status at Bandung Regency, West Java, Indonesia. These children were included in the population frame for a cohort study of vitamin D deficiency, vitamin D binding protein, and its impact on neurodevelopmental functions. A cross-sectional study was nested in the cohort study. The subjects were selected by stratified random sampling of 270 villages to meet the required number of samples. Medical doctors reassessed the anthropometric measurements and performed guided interviews to collect associated factors for IDA and CAS. Erythrocyte profiles of the children were examined from venous blood. : One hundred and ninety-four subjects were included in the analysis, among which 54.1% were stunted. Anemia was present in 40.7% of the subjects, largely due to IDA (87.3%). A wasting child and the factor of low paternal education (up to elementary school) were associated with IDA (aOR of 7.12 and aOR of 3.32, < 0.05, respectively). Co-occurrence of anemia and stunting was found in 41/194 (21.1%) subjects, but it did not show significant association. : Anemia and stunting were prevalent among children aged 6-24 months, but no associations were found between anemia and stunting in this study. Iron deficiency was the main cause of anemia, and it was associated with wasting and low paternal education.

摘要

贫血,尤其是缺铁性贫血(IDA)和发育迟缓,仍然是印度尼西亚幼儿期显著的公共卫生挑战;然而,相关研究仍然很少。本研究旨在确定贫血与发育迟缓的共现情况(CAS)、其患病率及相关因素,并描述红细胞参数。:印度尼西亚西爪哇省万隆县的助产士识别出约2200名6至24个月大的儿童存在营养状况问题。这些儿童被纳入一项关于维生素D缺乏、维生素D结合蛋白及其对神经发育功能影响的队列研究的人群框架中。一项横断面研究嵌套在该队列研究中。通过对270个村庄进行分层随机抽样来选择研究对象,以满足所需的样本数量。医生重新评估了人体测量数据,并进行了指导性访谈以收集与IDA和CAS相关的因素。从静脉血中检测儿童的红细胞谱。:194名研究对象纳入分析,其中54.1%发育迟缓。40.7%的研究对象存在贫血,主要原因是IDA(87.3%)。消瘦儿童和父亲低教育水平(小学及以下)因素与IDA相关(调整后比值比分别为7.12和3.32,均<0.05)。41/194(21.1%)的研究对象存在贫血与发育迟缓共现情况,但未显示出显著关联。:贫血和发育迟缓在6至24个月大的儿童中普遍存在,但本研究未发现贫血与发育迟缓之间存在关联。缺铁是贫血的主要原因,且与消瘦和父亲低教育水平相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/defb/12110383/fd70508a10e0/children-12-00638-g001.jpg

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