Inpatient Department of Ultrasound, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150081, Heilongjiang, China.
Department of Mammary Surgery, The Second Affiliated Hospital of Harbin Medical University, NO. 246 Xuefu Road, Nangang District, Harbin, 150081, Heilongjiang, China.
World J Surg. 2023 Aug;47(8):1961-1970. doi: 10.1007/s00268-023-07028-y. Epub 2023 May 6.
To explore the value of mixed reality (MR) in sentinel lymph node biopsy (SLNB) in patients with breast cancer.
A total of 300 patients with breast cancer who underwent SLNB enrolled and were randomly divided into two groups. In group A, only dye (an injection of methylene blue) was used to detect sentinel lymph nodes, while in group B MR was used for positioning in addition to dye. (MR localization method: Before the surgery, we built a 1:1 3D reconstruction model based on the patient's CT or MRI original data, and after the patient was injected with dye, we completed MR localization by overlapping the pre-marked image with the model.) RESULTS: During surgery, the detection time in group B was significantly shorter than in group A (3.62 ± 1.20 vs.7.87 ± 1.86; p < 0.001). At 1-month post-surgery follow-up, the incidence of pain in group B was lower than that in group A (2.70 vs. 8.28%, p = 0.036). The incidence of upper limb dysfunction was lower in group B than in group A (2.03 vs. 8.97%, p = 0.009). In terms of the incidence of pain, group B was better than group A (0.68 vs. 3.45%, p = 0.094). The satisfaction of the two groups was scored, and the results showed that group B was better than group A (4.04 ± 0.91 vs.3.32 ± 0.94, p < 0.001).
The application of MR to SLNB in breast cancer can significantly reduce the detection time and the occurrence of complications and improve patient satisfaction.
探索混合现实（MR）在乳腺癌前哨淋巴结活检（SLNB）中的应用价值。
选取 300 例接受 SLNB 的乳腺癌患者，随机分为两组。A 组仅使用染料（亚甲蓝注射）检测前哨淋巴结，B 组在染料定位的基础上联合使用 MR 进行定位。（MR 定位方法：术前，我们根据患者的 CT 或 MRI 原始数据建立 1:1 的 3D 重建模型，在患者注射染料后，通过将预标记的图像与模型重叠来完成 MR 定位。）
手术中，B 组的检测时间明显短于 A 组（3.62±1.20 比 7.87±1.86；p<0.001）。术后 1 个月随访时，B 组疼痛发生率低于 A 组（2.70 比 8.28%，p=0.036）。B 组上肢功能障碍发生率低于 A 组（2.03 比 8.97%，p=0.009）。在疼痛发生率方面，B 组优于 A 组（0.68 比 3.45%，p=0.094）。对两组患者的满意度进行评分，结果显示 B 组优于 A 组（4.04±0.91 比 3.32±0.94，p<0.001）。
将 MR 应用于乳腺癌 SLNB 中可以显著缩短检测时间，减少并发症的发生，提高患者满意度。
