Division of Health Sciences, Osaka University, Graduate School of Medicine, 1-7 Yamada, Suita, Osaka, 565-0871, Japan.
Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Osaka, Japan.
BMC Geriatr. 2023 May 6;23(1):277. doi: 10.1186/s12877-023-03993-0.
Factors associated with weight loss in community-dwelling older people have been reported in several studies, but few studies have examined factors associated with weight loss by age groups. The purpose of this study was to clarify factors associated with weight loss by age in community-dwelling older people through a longitudinal study.
Participants in the SONIC study (Longitudinal Epidemiological Study of the Elderly) were community-dwelling people aged 70 or older. The participants were divided into two groups: 5% weight loss and maintenance groups, and compared. In addition, we examined factors affecting weight loss by age. The analysis method used was the χ test, and the t-test was used for comparison of the two groups. Factors associated with 5% weight loss at 3 years were examined using logistic regression analysis with sex, age, married couple, cognitive function, grip strength, and the serum albumin level as explanatory variables.
Of the 1157 subjects, the proportions showing 5% weight loss after 3 years among all subjects, those aged 70 years, 80 years, and 90 years, were 20.5, 13.8, 26.8, and 30.5%, respectively. In logistic regression analysis, factors associated with 5% weight loss at 3 years by age were influenced by BMI of 25 or higher (OR = 1.90, 95%CI = 1.08-3.34, p = 0.026), a married couple (OR = 0.49, 95% = 0.28-0.86, p = 0.013), serum albumin level below 3.8 g/dL (OR = 10.75, 95% = 1.90-60.73, p = 0.007) at age 70, and the grip strength at age 90 (OR = 1.24, 95%CI = 1.02-1.51, p = 0.034), respectively.
The results suggest that factors associated with weight loss by age in community-dwelling older people through a longitudinal study differ by age. In the future, this study will be useful to propose effective interventions to prevent factors associated with weight loss by age in community-dwelling older people.
已有多项研究报道了与社区居住的老年人体重减轻相关的因素,但很少有研究按年龄组检查与体重减轻相关的因素。本研究的目的是通过一项纵向研究阐明与社区居住的老年人体重减轻相关的因素。
SONIC 研究(老年人纵向流行病学研究)的参与者为 70 岁或以上的社区居住者。将参与者分为体重减轻 5%和维持组两组进行比较。此外,我们还检查了按年龄分组的体重减轻的影响因素。分析方法采用卡方检验,两组比较采用 t 检验。使用逻辑回归分析,以性别、年龄、已婚夫妇、认知功能、握力和血清白蛋白水平作为解释变量,检查与 3 年内体重减轻 5%相关的因素。
在 1157 名受试者中,所有受试者在 3 年内体重减轻 5%的比例分别为 70 岁、80 岁、90 岁受试者的 20.5%、13.8%、26.8%和 30.5%。在逻辑回归分析中,年龄相关的 3 年内体重减轻 5%的因素受 BMI 为 25 或更高(OR=1.90,95%CI=1.08-3.34,p=0.026)、已婚夫妇(OR=0.49,95%CI=0.28-0.86,p=0.013)、70 岁时血清白蛋白水平低于 3.8g/dL(OR=10.75,95%CI=1.90-60.73,p=0.007)和 90 岁时握力(OR=1.24,95%CI=1.02-1.51,p=0.034)的影响。
结果表明,通过纵向研究,社区居住的老年人体重减轻与年龄相关的因素因年龄而异。未来,这项研究将有助于提出有效的干预措施,以防止社区居住的老年人与年龄相关的体重减轻因素。