Department of Ophthalmology, Skåne University Hospital, Department of Clinical Sciences, Lund University, Lund, Sweden.
Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.
BMC Ophthalmol. 2023 May 8;23(1):201. doi: 10.1186/s12886-023-02930-4.
To investigate whether the repeatability of measurements with the Pentacam HR in patients with keratoconus is improved by patients gaining more experience of the measurement situation. Such an improvement could enhance the accuracy with which progressive keratoconus can be detected.
Four replicate measurements were performed on Day 0 and on Day 3. Parameters commonly used in the diagnosis of progressive keratoconus were included in the analysis, namely the flattest central keratometry value (K1), the steepest central keratometry value (K2), the maximum keratometry value (Kmax), and the parameters A, B and C from the Belin ABCD Progression Display. In addition, quality parameters used by the Pentacam HR to assess the quality of the measurements were included, namely the analysed area (front + back), 3D (front + back), XY, Z, and eye movements.
Neither the diagnostic parameters nor the quality parameters showed any statistically significant improvement on Day 3 compared to Day 0. The quality parameter "eye movements" deteriorated significantly with increasing Kmax.
Gaining experience of the measurement situation did not increase the accuracy of the measurements. Further investigations should be performed to determine whether the increasing number of eye movements with increasing disease severity has a negative effect on the repeatability of the measurements.
为了研究角膜膨隆患者对测量情况的经验增加是否会提高 Pentacam HR 测量的可重复性。这种改进可以提高检测进展性角膜膨隆的准确性。
在第 0 天和第 3 天分别进行 4 次重复测量。分析中包括常用于诊断进展性角膜膨隆的参数,即最平坦中央角膜曲率值(K1)、最陡峭中央角膜曲率值(K2)、最大角膜曲率值(Kmax)以及 Belin ABCD 进展显示中的参数 A、B 和 C。此外,还包括 Pentacam HR 用于评估测量质量的质量参数,即分析区域(前+后)、3D(前+后)、XY、Z 和眼球运动。
与第 0 天相比,第 3 天的诊断参数和质量参数均无统计学意义上的改善。质量参数“眼球运动”随着 Kmax 的增加显著恶化。
对测量情况的经验增加并未提高测量的准确性。应进一步进行研究,以确定随着疾病严重程度的增加,眼球运动次数的增加是否对测量的可重复性有负面影响。