多次复发性缺血性中风的危险因素。
Risk factors for multiple recurrent ischemic strokes.
作者信息
Uzuner Nevzat, Uzuner Gulnur Tekgol
机构信息
Department of Neurology, Eskisehir Osmangazi University, Turkey.
出版信息
Brain Circ. 2023 Mar 24;9(1):21-24. doi: 10.4103/bc.bc_73_22. eCollection 2023 Jan-Mar.
BACKGROUND
Cardiovascular diseases, hypertension, diabetes mellitus, dyslipidemia, and atrial fibrillation are the most common modifiable risk factors for recurrent ischemic stroke. In this study, we aimed to find the risk factors associated with more than two recurrent ischemic strokes after the first-ever stroke.
METHODS
We collected the ischemic stroke patients in our stroke registry data bank, and the eligible patients were followed for recurrent ischemic stroke after 2008. Our study consisted of 927 patients who were followed up for 9 years after the first-ever stroke.
RESULTS
We found that 185 (20%) patients had a recurrent ischemic stroke, and another 32 (3.5%) patients had more than one recurrence after the first-ever ischemic stroke. The mean time for the first stroke recurrence was 1 year, and the mean time for the multiple stroke recurrences was 3 years. Significant risk factors for multiple recurrences were congestive heart disease ( < 0.015) and diabetes mellitus ( < 0.006).
CONCLUSIONS
We concluded that even with the appropriate treatments, patients with congestive heart disease and diabetes mellitus have a higher rate of multiple recurrences for ischemic stroke after the first-ever ischemic stroke, indicating that more attention should be paid to this issue.
背景
心血管疾病、高血压、糖尿病、血脂异常和心房颤动是复发性缺血性卒中最常见的可改变风险因素。在本研究中，我们旨在找出首次卒中后发生两次以上复发性缺血性卒中的相关风险因素。
方法
我们收集了卒中登记数据库中的缺血性卒中患者，并对符合条件的患者自2008年起随访其复发性缺血性卒中情况。我们的研究包括927例首次卒中后随访9年的患者。
结果
我们发现185例（20%）患者发生了复发性缺血性卒中，另有32例（3.5%）患者在首次缺血性卒中后复发不止一次。首次卒中复发的平均时间为1年，多次卒中复发的平均时间为3年。多次复发的显著风险因素是充血性心力衰竭（<0.015）和糖尿病（<0.006）。
结论
我们得出结论，即使进行了适当治疗，充血性心力衰竭和糖尿病患者在首次缺血性卒中后发生多次缺血性卒中复发的几率更高，这表明应更加关注这一问题。
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