Hallman Isa, Karikoski Ninja, Kareskoski Maria
Department of Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.
Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.
Front Vet Sci. 2023 Apr 20;10:1180622. doi: 10.3389/fvets.2023.1180622. eCollection 2023.
Obesity is a growing welfare concern in modern equine populations and predisposes horses to disturbances in energy metabolism such as insulin dysregulation. However, equine metabolic syndrome has only been recognized in recent decades. Functioning energy metabolism is pivotal to normal body homeostasis and affects essentially all organ systems, including reproduction. Previous literature suggests that obesity has an effect not only on the reproductive processes in mares but also on offspring health, predisposing the offspring to later-onset orthopedic and metabolic problems. This review focuses on the effects of obesity, insulin dysregulation and hyperinsulinemia on the reproductive functions of mares and the implications on foal health before and after birth. The points of interest are the cyclicity and ovarian function, uterine environment, gestation, the postpartum period, and the newborn foal. The aim is to review the current state of knowledge, and identify outstanding questions that could stimulate future research. This topic is important not only from the equine industry and production perspective but is also relevant for the welfare of future populations and individuals.
肥胖是现代马群中日益受到关注的福利问题，使马易出现能量代谢紊乱，如胰岛素调节异常。然而，马代谢综合征直到最近几十年才被认识到。正常的能量代谢对维持身体内环境稳定至关重要，并且基本上影响所有器官系统，包括生殖系统。先前的文献表明，肥胖不仅对母马的生殖过程有影响，还会影响后代健康，使后代易患后期出现的骨科和代谢问题。本综述聚焦于肥胖、胰岛素调节异常和高胰岛素血症对母马生殖功能的影响以及对出生前后驹健康的影响。关注的要点包括发情周期和卵巢功能、子宫环境、妊娠、产后时期以及新生驹。目的是回顾当前的知识状况，并确定可能激发未来研究的突出问题。这个主题不仅从养马业和生产的角度来看很重要，而且对于未来马群和个体的福利也很相关。
