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原发性直肠肛管印戒细胞黑素瘤:1例报告

Primary signet‑ring cell melanoma of the anorectum: A case report.

作者信息

Ma Hongyan, Shi Shuai, Zhang Zhigang, Liu Honggang

机构信息

Department of Pathology, Key Laboratory of Head and Neck Molecular Diagnosis Pathology, Beijing TongRen Hospital, Capital Medical University, Beijing 100000, P.R. China.

Department of Pathology, Cangzhou People's Hospital, Cangzhou, Hebei 061000, P.R. China.

出版信息

Oncol Lett. 2023 Apr 13;25(6):220. doi: 10.3892/ol.2023.13806. eCollection 2023 Jun.

DOI:10.3892/ol.2023.13806
PMID:37153063
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10157357/
Abstract

Malignant melanoma is one of the most common malignant tumors. Although its incidence rate is generally low among the Chinese population, it has grown rapidly in recent years. The incidence of primary malignant melanoma in the digestive tract is very low. The incidence in the esophagus and rectum are more common, while reports in the colon are only reported in <10 cases. Primary signet ring cell carcinoma of the rectum is also a rare and unique tumor. This paper reports a case of rectal malignant melanoma with signet ring cell carcinoma.

摘要

恶性黑色素瘤是最常见的恶性肿瘤之一。虽然其发病率在中国人群中总体较低,但近年来呈快速增长趋势。消化道原发性恶性黑色素瘤的发病率非常低。在食管和直肠的发病率较为常见,而结肠的报道仅有不到10例。直肠原发性印戒细胞癌也是一种罕见且独特的肿瘤。本文报道1例直肠恶性黑色素瘤伴印戒细胞癌的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20b0/10157357/783a7c0cd8aa/ol-25-06-13806-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20b0/10157357/783a7c0cd8aa/ol-25-06-13806-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20b0/10157357/783a7c0cd8aa/ol-25-06-13806-g00.jpg

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本文引用的文献

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Cancers (Basel). 2021 Jan 9;13(2):221. doi: 10.3390/cancers13020221.
2
Identification of recurrent mutational events in anorectal melanoma.肛管黑色素瘤中复发性突变事件的鉴定
Mod Pathol. 2017 Feb;30(2):286-296. doi: 10.1038/modpathol.2016.179. Epub 2016 Oct 14.
3
Signet-ring cell melanoma: a potential diagnostic pitfall.印戒细胞黑色素瘤:一个潜在的诊断陷阱。
The Cytodiagnosis of Amelanotic Primary Signet Ring Cell Melanoma at the Unusual Site of the Axilla: A Case Report of a Rare Entity.
腋窝罕见部位无色素性原发性印戒细胞黑色素瘤的细胞诊断:1例罕见病例报告
Cureus. 2023 Nov 13;15(11):e48714. doi: 10.7759/cureus.48714. eCollection 2023 Nov.
Am J Dermatopathol. 2014 Dec;36(12):985-8. doi: 10.1097/DAD.0000000000000015.
4
Phase II, open-label, single-arm trial of imatinib mesylate in patients with metastatic melanoma harboring c-Kit mutation or amplification.甲磺酸伊马替尼治疗伴有 c-Kit 突变或扩增的转移性黑色素瘤患者的 II 期、开放标签、单臂试验。
J Clin Oncol. 2011 Jul 20;29(21):2904-9. doi: 10.1200/JCO.2010.33.9275. Epub 2011 Jun 20.
5
Pathogenesis, diagnosis and management of primary melanoma of the colon.结肠原发性黑色素瘤的发病机制、诊断与治疗。
World J Surg Oncol. 2011 Feb 1;9:14. doi: 10.1186/1477-7819-9-14.
6
Primary cutaneous signet-ring cell melanoma with pseudoglandular features, spindle cells and oncocytoid changes.具有假腺管特征、梭形细胞和嗜酸性细胞样改变的原发性皮肤印戒细胞黑色素瘤。
Am J Dermatopathol. 2009 Feb;31(1):81-3. doi: 10.1097/DAD.0b013e3181814c5e.
7
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J Cutan Pathol. 2008 May;35(5):433-44. doi: 10.1111/j.1600-0560.2007.00891.x.
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Primary cutaneous signet-ring cell melanoma: a clinico-pathologic and immunohistochemical study of two cases.原发性皮肤印戒细胞黑色素瘤:两例临床病理及免疫组织化学研究
Am J Dermatopathol. 2003 Oct;25(5):418-22. doi: 10.1097/00000372-200310000-00007.
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Histopathology. 2000 May;36(5):387-402. doi: 10.1046/j.1365-2559.2000.00894.x.
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