Mesalles Maria E, Rao Shiavax J, Sagheer Usman
Internal Medicine, MedStar Union Memorial Hospital, Baltimore, USA.
Cureus. 2023 Mar 23;15(3):e36607. doi: 10.7759/cureus.36607. eCollection 2023 Mar.
The mechanism of arterial thrombosis in coronavirus disease 2019 (COVID-19) is not completely understood and is attributed to the complex interactions of endothelial injury, platelet hyperactivation, and activated pro-inflammatory cytokines. Management strategies may include a combination of surgery and anticoagulation, or anticoagulation alone. A 56-year-old woman with recent COVID-19 infection presented with chest pain and dyspnea. Chest CT angiography (CTA) and aortic magnetic resonance imaging revealed an intraluminal thrombus in the mid ascending aorta. A multidisciplinary team decided on heparin infusion. She was transitioned to apixaban and a three-month interval outpatient CTA revealed complete resolution of the aortic thrombus.
2019冠状病毒病(COVID-19)中动脉血栓形成的机制尚未完全明确,其被认为是内皮损伤、血小板过度活化和促炎细胞因子活化之间复杂相互作用的结果。治疗策略可能包括手术与抗凝联合使用,或单独使用抗凝治疗。一名近期感染COVID-19的56岁女性出现胸痛和呼吸困难。胸部CT血管造影(CTA)和主动脉磁共振成像显示升主动脉中段管腔内有血栓。一个多学科团队决定给予肝素输注。她随后改用阿哌沙班,三个月后的门诊CTA显示主动脉血栓完全消失。