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新冠与莱姆病:一例长期新冠病例研究。

Corona With Lyme: A Long COVID Case Study.

作者信息

Thor Danielle C, Suarez Sergio

机构信息

Internal Medicine, Touro College of Osteopathic Medicine, New York, USA.

Osteopathic Medicine, Touro College of Osteopathic Medicine, New York, USA.

出版信息

Cureus. 2023 Mar 24;15(3):e36624. doi: 10.7759/cureus.36624. eCollection 2023 Mar.

DOI:10.7759/cureus.36624
PMID:37155451
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10122830/
Abstract

The longevity of the coronavirus disease 2019 (COVID-19) pandemic has necessitated continued discussion about the long-term impacts of SARS-CoV-2 infection. Many who develop an acute COVID-19 infection will later face a constellation of enduring symptoms of varying severity, otherwise known as long COVID. As the pandemic reaches its inevitable endemicity, the long COVID patient population will undoubtedly grow and require improved recognition and management. The case presented describes the three-year arc of a previously healthy 26-year-old female medical student from initial infection and induction of long COVID symptomology to near-total remission of the disease. In doing so, the course of this unique post-viral illness and the trials and errors of myriad treatment options will be chronologized, thereby contributing to the continued demand for understanding this mystifying disease.

摘要

2019冠状病毒病(COVID-19)大流行的持久性使得人们有必要继续讨论严重急性呼吸综合征冠状病毒2感染的长期影响。许多感染COVID-19急性期的人随后将面临一系列严重程度各异的持续症状,也就是所谓的长期新冠。随着大流行不可避免地进入地方流行阶段,长期新冠患者群体无疑会增加,需要更好地识别和管理。本文介绍的病例描述了一名26岁健康的女医学生从最初感染、出现长期新冠症状到疾病几乎完全缓解的三年历程。这样做的话,这种独特的病毒后疾病的病程以及无数治疗方案的尝试与失误将按时间顺序记录下来,从而满足人们持续的需求,即了解这种令人困惑的疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dddc/10122830/a7d769a8338c/cureus-0015-00000036624-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dddc/10122830/a7d769a8338c/cureus-0015-00000036624-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dddc/10122830/a7d769a8338c/cureus-0015-00000036624-i01.jpg

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本文引用的文献

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BMJ Med. 2023 Feb 1;2(1):e000385. doi: 10.1136/bmjmed-2022-000385. eCollection 2023.
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Long COVID: major findings, mechanisms and recommendations.长新冠:主要发现、机制和建议。
Nat Rev Microbiol. 2023 Mar;21(3):133-146. doi: 10.1038/s41579-022-00846-2. Epub 2023 Jan 13.
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Long COVID and the risk of suicide.长期新冠与自杀风险。
Gen Hosp Psychiatry. 2023 Jan-Feb;80:66-67. doi: 10.1016/j.genhosppsych.2022.12.001. Epub 2022 Dec 5.
4
Lots of long COVID treatment leads, but few are proven.治疗长期新冠有很多线索,但经证实的却很少。
Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2213524119. doi: 10.1073/pnas.2213524119. Epub 2022 Sep 1.
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Postural orthostatic tachycardia syndrome as a sequela of COVID-19.COVID-19 后体位性心动过速综合征。
Heart Rhythm. 2022 Nov;19(11):1880-1889. doi: 10.1016/j.hrthm.2022.07.014. Epub 2022 Jul 16.
6
Estrogen hormone is an essential sex factor inhibiting inflammation and immune response in COVID-19.雌激素是一种重要的性激素,可抑制 COVID-19 中的炎症和免疫反应。
Sci Rep. 2022 Jun 8;12(1):9462. doi: 10.1038/s41598-022-13585-4.
7
The Relationship between Physical Activity and Long COVID: A Cross-Sectional Study.体力活动与长新冠之间的关系:一项横断面研究。
Int J Environ Res Public Health. 2022 Apr 22;19(9):5093. doi: 10.3390/ijerph19095093.
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Global Prevalence of Post-Coronavirus Disease 2019 (COVID-19) Condition or Long COVID: A Meta-Analysis and Systematic Review.全球新型冠状病毒病 2019(COVID-19)后状况或长新冠的流行率:一项荟萃分析和系统评价。
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