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[白细胞干扰素对肺部疾病中支气管肺泡吞噬细胞功能状态的影响]

[Effect of leukocytic interferon on the functional state of bronchoalveolar phagocytes in lung diseases].

作者信息

Chernushenko E F, Belianovskaia T I, Kuznetsova L V, Shpak O I, Shatrov V A

出版信息

Ter Arkh. 1986;58(4):83-5.

PMID:3715762
Abstract

A study was made of the effect of leukocytic interferon on the phagocytic activity of alveolar macrophages and neutrophils in patients with chronic bronchitis, tuberculosis and sarcoidosis of the lungs. Cells isolated from the patients' bronchoalveolar washing off were used. It was concluded that short-term incubation of macrophages and neutrophils with interferon resulted in phagocytosis enhancement and increased intensity of metabolic processes in them. Interferon produced the most noticeable effect on cells with an initially reduced absorption capacity.

摘要

对白细胞干扰素对慢性支气管炎、肺结核和肺部结节病患者肺泡巨噬细胞和中性粒细胞吞噬活性的影响进行了研究。使用从患者支气管肺泡灌洗物中分离出的细胞。得出的结论是,巨噬细胞和中性粒细胞与干扰素的短期孵育导致吞噬作用增强,并且它们的代谢过程强度增加。干扰素对初始吸收能力降低的细胞产生的影响最为明显。

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Ter Arkh. 1986;58(4):83-5.
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