Ehrich M, Gross W B
Toxicol Lett. 1986 Apr;31(1):9-13. doi: 10.1016/0378-4274(86)90188-8.
Adult White Leghorn roosters maintained for 3 months in an environment of low social stress (LSS) were given triorthotolyl phosphate (TOTP), 180 mg/kg po, 24 h after initial exposure to either an environment of high social stress (HSS) or exogenously administered corticosterone (200 ppm in diet). The environment of HSS or the administration of corticosterone were continued for 10 days after TOTP administration. It was noted that the heterophil/lymphocyte ratio, a hematological indicator of stress, was similar in both groups and both had similar scores for clinical signs of delayed neuropathy. Both heterophil/lymphocyte ratios and clinical scores were significantly lower in chickens kept in the LSS environment and not fed corticosterone than in chickens kept in the HSS environment or fed corticosterone.
将成年白来航公鸡在低社会应激（LSS）环境中饲养3个月后，在初次暴露于高社会应激（HSS）环境或外源给予皮质酮（饮食中200 ppm）24小时后，口服三邻甲苯基磷酸酯（TOTP），剂量为180 mg/kg。给予TOTP后，HSS环境或皮质酮给药持续10天。结果发现，作为应激血液学指标的嗜异性粒细胞/淋巴细胞比值在两组中相似，且两组在迟发性神经病变临床体征方面得分相似。与饲养在HSS环境或给予皮质酮的鸡相比，饲养在LSS环境且未给予皮质酮的鸡的嗜异性粒细胞/淋巴细胞比值和临床评分均显著更低。
