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用于光催化应用的氨基功能化核壳磁性纳米粒子的设计与制备及其细胞毒性效应研究

Design and preparation of amino-functionalized core-shell magnetic nanoparticles for photocatalytic application and investigation of cytotoxicity effects.

作者信息

Sabouri Zahra, Sabouri Mohammad, Moghaddas Samaneh Sadat Tabrizi Hafez, Darroudi Majid

机构信息

Department of Medical Biotechnology and Nanotechnology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Medical Toxicology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

J Environ Health Sci Eng. 2022 Nov 30;21(1):93-105. doi: 10.1007/s40201-022-00842-x. eCollection 2023 Jun.

Abstract

The goal of the current paper was a synthesis of Amino-functionalized FeO@SiO core-shell magnetic nanoparticles as a unique efficient photocatalyst for removing organic dyes from aqueous environments. The magnetic FeO@SiO core-shell was produced by a silica source to avoid aggregation by the co-precipitation method. Next, functionalized by using 3-Aminopropyltriethoxysilane (APTES) via a post-synthesis link. The chemical structure, magnetic properties, and shape of the manufactured photocatalyst (FeO@SiO-NH) were described by XRD, VSM, FT-IR, FESEM, EDAX, and DLS/Zeta potential analyses. The XRD findings approved the successful synthesis of nanoparticles. The photocatalytic activity of FeO@SiO-NH nanoparticles was examined for MB degradation and the degradation performance was about 90% in the optimum conditions. Also, the cytotoxicity of FeO, FeO@SiO core-shell, and FeO@SiO-NH nanoparticles was examined on CT-26 cells using an MTT assay, the finding has shown that nanoparticles can be used for inhibiting cancer cells.

摘要

本文的目标是合成氨基功能化的FeO@SiO核壳磁性纳米颗粒,作为一种独特的高效光催化剂,用于从水性环境中去除有机染料。磁性FeO@SiO核壳是通过二氧化硅源采用共沉淀法制备的,以避免聚集。接下来,通过后合成连接使用3-氨丙基三乙氧基硅烷(APTES)进行功能化。通过XRD、VSM、FT-IR、FESEM、EDAX和DLS/ζ电位分析对制备的光催化剂(FeO@SiO-NH)的化学结构、磁性和形状进行了描述。XRD结果证实了纳米颗粒的成功合成。研究了FeO@SiO-NH纳米颗粒对亚甲基蓝降解的光催化活性,在最佳条件下,降解性能约为90%。此外,使用MTT法检测了FeO、FeO@SiO核壳和FeO@SiO-NH纳米颗粒对CT-26细胞的细胞毒性,结果表明纳米颗粒可用于抑制癌细胞。

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