Zhu Nan, Ji Haining, Yu Peng, Niu Jiaqi, Farooq M U, Akram M Waseem, Udego I O, Li Handong, Niu Xiaobin
School of Materials and Energy, University of Electronic Science and Technology of China, Chengdu 610054, China.
Institute of Fundamental and Frontier Science, University of Electronic Science and Technology, Chengdu 610054, China.
Nanomaterials (Basel). 2018 Oct 9;8(10):810. doi: 10.3390/nano8100810.
Functionalized iron oxide nanoparticles (IONPs) are of great interest due to wide range applications, especially in nanomedicine. However, they face challenges preventing their further applications such as rapid agglomeration, oxidation, etc. Appropriate surface modification of IONPs can conquer these barriers with improved physicochemical properties. This review summarizes recent advances in the surface modification of IONPs with small organic molecules, polymers and inorganic materials. The preparation methods, mechanisms and applications of surface-modified IONPs with different materials are discussed. Finally, the technical barriers of IONPs and their limitations in practical applications are pointed out, and the development trends and prospects are discussed.
功能化氧化铁纳米颗粒(IONPs)因其广泛的应用而备受关注,尤其是在纳米医学领域。然而,它们面临着阻碍其进一步应用的挑战,如快速团聚、氧化等。对IONPs进行适当的表面修饰可以克服这些障碍,并改善其物理化学性质。本文综述了近年来用小分子有机物、聚合物和无机材料对IONPs进行表面修饰的研究进展。讨论了用不同材料对IONPs进行表面修饰的制备方法、作用机制及应用。最后,指出了IONPs的技术障碍及其在实际应用中的局限性,并探讨了其发展趋势和前景。
Nanomaterials (Basel). 2018-10-9
Sci Technol Adv Mater. 2015-4-28
Materials (Basel). 2022-1-10
J Nanobiotechnology. 2024-1-8
Front Drug Deliv. 2025-7-30
Drug Deliv Transl Res. 2025-6-18
Nat Rev Bioeng. 2025-3
Nanomaterials (Basel). 2025-1-17
J Mater Chem B. 2014-2-14
Chem Commun (Camb). 2017-11-14
Mater Sci Eng C Mater Biol Appl. 2017-9-1
Int J Nanomedicine. 2017-4-27
Nanoscale Res Lett. 2017-12
Mater Sci Eng C Mater Biol Appl. 2017-6-1