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巴西若因维莱市与心房颤动相关的心源性脑梗死发病率。

Incidence of cardioembolic stroke related to atrial fibrillation in Joinville, Brazil.

机构信息

Hospital Municipal São José, Departamento de Medicina Interna, Serviço de Neurologia, Joinville SC, Brazil.

Universidade da Região de Joinville, Departamento de Medicina, Joinville SC, Brazil.

出版信息

Arq Neuropsiquiatr. 2023 Apr;81(4):329-333. doi: 10.1055/s-0043-1767821. Epub 2023 May 9.

DOI:10.1055/s-0043-1767821
PMID:37160136
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10169222/
Abstract

BACKGROUND

Atrial fibrillation (AF) is an important cause of cardioembolic stroke, and population aging has increased its prevalence.

OBJECTIVE

To evaluate the incidence of cardioembolic stroke caused by AF in the city of Joinville, Brazil, as well as previous diagnoses and use of medication.

METHODS

Between 2017 and 2020 we extracted data from the population-based Joinville Stroke Registry. Demographic characteristics, diagnosis of AF, and patterns of medication use were collected, and the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) system was used to classify the etiology.

RESULTS

There were 3,303 cases of ischemic stroke, 593 of which were cardioembolic, and 360 had AF. Of the patients with AF, 258 (71.6%) had a previous diagnosis of the disease, and 102 (28.3%) were newly diagnosed after the stroke. Among patients with a previously-diagnosed AF, 170 (47.2%) were using anticoagulants, and 88 (24.4%) were using other medications.

CONCLUSION

During the analyzed period, ischemic stroke caused by AF was a significant burden on the population of Joinville, and a considerable number of patients had undiagnosed or untreated AF.

摘要

背景

心房颤动(AF)是心源性脑栓塞的重要病因,人口老龄化使其发病率增加。

目的

评估巴西若因维莱市 AF 导致心源性脑栓塞的发生率,以及既往诊断和药物使用情况。

方法

我们于 2017 年至 2020 年期间从基于人群的若因维莱卒中登记处提取数据。收集人口统计学特征、AF 诊断和药物使用模式,并采用试验性急性脑卒中治疗中 ORG 10172(TOAST)系统对病因进行分类。

结果

共纳入 3303 例缺血性卒中患者,其中 593 例为心源性脑栓塞,360 例为 AF。在有 AF 的患者中,258 例(71.6%)既往诊断过该病,102 例(28.3%)在卒中后新诊断。在既往诊断为 AF 的患者中,170 例(47.2%)正在使用抗凝药物,88 例(24.4%)正在使用其他药物。

结论

在分析期间,AF 导致的缺血性卒中给若因维莱市人群带来了沉重负担,相当数量的患者存在未诊断或未治疗的 AF。

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