Department of Pharmaceutical Technology, Kulliyyah of Pharmacy, International Islamic University Malaysia (IIUM), Jalan Sultan Ahmad Shah, 25200, Kuantan, Pahang, Malaysia.
IKOP SdnBhd, Kulliyyah of Pharmacy, International Islamic University Malaysia (IIUM), Jalan Sultan Ahmad Shah, 25200, Kuantan, Pahang, Malaysia.
AAPS PharmSciTech. 2023 May 9;24(5):116. doi: 10.1208/s12249-023-02570-3.
Three-dimensional (3D) printing technology has presently been explored widely in the field of pharmaceutical research to produce various conventional as well as novel dosage forms such as tablets, capsules, oral films, pellets, subcutaneous implants, scaffolds, and vaginal rings. The use of this innovative method is a good choice for its advanced technologies and the ability to make tailored medicine specifically for individual patient. There are many 3D printing systems that are used to print tablets, implants, and vaginal rings. Among the available systems, the fused deposition modeling (FDM) is widely utilized. The FDM has been regarded as the best choice of printer as it shows high potential in the production of tablets as a unit dose in 3D printing medicine manufacturing. In order to design a 3D-printed tablet or other dosage forms, the physicochemical properties of polymers play a vital role. One should have proper knowledge about the polymer's properties so that one can select appropriate polymers in order to design 3D-printed dosage form. This review highlighted the various physicochemical properties of polymers that are currently used as filaments in 3D printing. In this manuscript, the authors also discussed various systems that are currently adopted in the 3D printing.
三维（3D）打印技术目前在药物研究领域得到了广泛的探索，可用于生产各种常规和新型剂型，如片剂、胶囊、口腔膜、丸剂、皮下植入物、支架和阴道环。这种创新方法的使用是一个不错的选择，因为它具有先进的技术和为个体患者定制药物的能力。有许多 3D 打印系统可用于打印片剂、植入物和阴道环。在可用的系统中，熔融沉积建模（FDM）被广泛使用。FDM 被认为是打印机的最佳选择，因为它在 3D 打印药物制造中作为单位剂量生产片剂方面显示出很高的潜力。为了设计 3D 打印片剂或其他剂型，聚合物的物理化学性质起着至关重要的作用。人们应该对聚合物的性质有适当的了解，以便能够选择合适的聚合物来设计 3D 打印剂型。本文综述了目前用作 3D 打印丝材的聚合物的各种物理化学性质。在本文中，作者还讨论了目前在 3D 打印中采用的各种系统。
