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急性医院获得性有症状肺血栓栓塞症患者的危险因素。

Risk factors for patients with acute hospital-acquired symptomatic pulmonary thromboembolism.

机构信息

The Department of General Surgery, Ganzhou People's Hospital, Ganzho, 341000, Jiangxi, People's Republic of China.

出版信息

Sci Rep. 2023 May 9;13(1):7552. doi: 10.1038/s41598-023-34589-8.

DOI:10.1038/s41598-023-34589-8
PMID:37160945
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10169767/
Abstract

This study aimed to identify independent risk factors for acute hospital-acquired symptomatic pulmonary embolism (HA-SPE) by comparing the clinical data of HA-SPE and acute nonhospital-acquired symptomatic pulmonary embolism (NHA-SPE). A total of 292 patients were included in the analysis and divided into two groups: 191 patients had acute NHA-SPE, and 101 patients had acute HA-SPE. The average age of these 292 patients was 63.2 years, and the sample included 145 males. Multivariate analysis showed that malignant tumour (OR, 3.811; 95% CI [1.914-7.586], P = 0.000), recent surgery (OR, 7.310; 95% CI 3.392-15.755], P = 0.000), previous VTE (OR, 5.973; 95% CI 2.194 16.262], P = 0. 000), and the length of stay (LOS) (OR, 1.075; 95% CI [1.040-1.111], P = 0.000) were independent risk factors for acute HA-AEP. The c-statistic for this model was 0.758 (95% CI [0.698-0.800], P < 0.0001). The K-M curve showed that the hazard ratio (HR) of the HA group to the NHA group in all-cause mortality was 3.807 (95% CI [1.987, 7.295], P = 0.0061). Strengthening the prevention and control of patients with these risk factors may reduce the incidence of acute HA-SPE.

摘要

本研究旨在通过比较急性医院获得性有症状肺栓塞（HA-SPE）和急性非医院获得性有症状肺栓塞（NHA-SPE）的临床数据，确定急性 HA-SPE 的独立危险因素。共纳入 292 例患者，分为两组：191 例患者为急性 NHA-SPE，101 例患者为急性 HA-SPE。这 292 例患者的平均年龄为 63.2 岁，样本中包括 145 名男性。多因素分析显示，恶性肿瘤（OR，3.811；95%CI[1.914-7.586]，P=0.000）、近期手术（OR，7.310；95%CI[3.392-15.755]，P=0.000）、既往 VTE（OR，5.973；95%CI[2.194-16.262]，P=0.000）和住院时间（LOS）（OR，1.075；95%CI[1.040-1.111]，P=0.000）是急性 HA-AEP 的独立危险因素。该模型的 C 统计量为 0.758（95%CI[0.698-0.800]，P<0.0001）。K-M 曲线显示，HA 组与 NHA 组全因死亡率的危险比（HR）为 3.807（95%CI[1.987,7.295]，P=0.0061）。加强对这些危险因素患者的预防和控制可能会降低急性 HA-SPE 的发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65bf/10169767/25444affcff8/41598_2023_34589_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65bf/10169767/36fcce1f4250/41598_2023_34589_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65bf/10169767/a26f291942a2/41598_2023_34589_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65bf/10169767/25444affcff8/41598_2023_34589_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65bf/10169767/36fcce1f4250/41598_2023_34589_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65bf/10169767/a26f291942a2/41598_2023_34589_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65bf/10169767/25444affcff8/41598_2023_34589_Fig3_HTML.jpg

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本文引用的文献

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2
Pulmonary embolism following urological non-oncological surgery: The clinical features, management, and long-term follow-up outcome from a tertiary hospital of China.泌尿外科非肿瘤手术后继发肺栓塞：来自中国一家三级医院的临床特征、治疗及长期随访结果
Front Surg. 2022 Sep 5;9:930968. doi: 10.3389/fsurg.2022.930968. eCollection 2022.
3
In-hospital prognosis of malignancy-related pulmonary embolism: an analysis of the national inpatient sample 2016-2018.
2016-2018 年全国住院患者样本分析：恶性肿瘤相关肺栓塞的住院预后。
J Thromb Thrombolysis. 2022 Nov;54(4):630-638. doi: 10.1007/s11239-022-02684-8. Epub 2022 Jul 25.
4
Effect of Prognostic Guided Management of Patients With Acute Pulmonary Embolism According to the European Society of Cardiology Risk Stratification Model.根据欧洲心脏病学会风险分层模型对急性肺栓塞患者进行预后指导管理的效果
Front Cardiovasc Med. 2022 Apr 12;9:872115. doi: 10.3389/fcvm.2022.872115. eCollection 2022.
5
Randomised comparative effectiveness trial of Pulmonary Embolism Prevention after hiP and kneE Replacement (PEPPER): the PEPPER trial protocol.髋关节和膝关节置换术后肺栓塞预防（PEPPER）随机对照有效性试验：PEPPER 试验方案。
BMJ Open. 2022 Mar 8;12(3):e060000. doi: 10.1136/bmjopen-2021-060000.
6
Development and validation of a prediction model to estimate risk of acute pulmonary embolism in deep vein thrombosis patients.开发和验证一种预测模型，以评估深静脉血栓形成患者发生急性肺栓塞的风险。
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7
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