Drumcheva M, Todorov D, Stoĭnov S, Nikolov N, Boneva M
Vutr Boles. 1986;25(2):14-7.
A method has been for counting the mastocytes on 0.1 mm2 of intestinal mucosa in patients with chronic enterocolitis, gluten enteropathy, ulcerous colitis in a stage of exacerbation and in controls. The comparison of the results obtained in the separate groups of patients reveal an increased number of mastocytes in gluten enteropathy--mean = 21.01 +/- 6 as compared with the chronic enterocolitis, where mean = 9.79 +/- 3.83 (p = 0.002). Higher values of mastocytes in rectal mucosa were observed in the patients with ulcerous mucosa--mean = 15.83 +/- 4.49 as compared with the control subjects with means = 3.67 +/- 0.99 (p = 0.001). those data admit the participation of mastocytes in the morbid process in patients with gluten enteropathy and with ulcerous colitis.
已经有一种方法用于对患有慢性小肠结肠炎、麸质过敏性肠病、处于加重期的溃疡性结肠炎的患者以及对照组患者的0.1平方毫米肠黏膜中的肥大细胞进行计数。对不同患者组所得结果的比较显示,麸质过敏性肠病患者的肥大细胞数量增加——平均值为21.01±6,而慢性小肠结肠炎患者的平均值为9.79±3.83(p = 0.002)。在溃疡性结肠炎患者的直肠黏膜中观察到更高的肥大细胞值——平均值为15.83±4.49,而对照组受试者的平均值为3.67±0.99(p = 0.001)。这些数据表明肥大细胞参与了麸质过敏性肠病和溃疡性结肠炎患者的发病过程。