Department of Microbiology and Immunology, Dartmouth Geisel School of Medicine, Hanover, NH 03756, USA.
Department of Microbiology and Immunology, Dartmouth Geisel School of Medicine, Hanover, NH 03756, USA.
Immunity. 2023 May 9;56(5):900-902. doi: 10.1016/j.immuni.2023.04.007.
Monocytes can differentiate into tissue-resident pleural macrophages, but the mechanisms underlying this process are not yet fully understood. In this issue of Immunity, Finlay et al. show that Th2 cytokines promote this differentiation in resistant mice infected with Litomosoides sigmodontis.
单核细胞可分化为组织驻留性胸膜巨噬细胞,但这一过程的机制尚不完全清楚。在本期《免疫》中,Finlay 等人表明,在感染旋毛虫的抗性小鼠中,Th2 细胞因子促进了这种分化。