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[支气管哮喘和慢性阻塞性肺疾病患者吸入技术评估]

[Assessment of inhalation technique in patients with bronchial asthma and chronic obstructive pulmonary disease].

作者信息

Trushenko N V, Stoliarevich A A, Andriukov B G, Nuralieva G S, Tsareva N A, Lavginova B B, Avdeev S N

机构信息

Sechenov First Moscow State Medical University (Sechenov University).

Federal Pulmonology Research Institute.

出版信息

Ter Arkh. 2023 Apr 26;95(3):210-216. doi: 10.26442/00403660.2023.03.202151.

Abstract

AIM

Investigate inhalation techniques using different inhalers types and their effect on the course of disease.

MATERIALS AND METHODS

This cross-sectional study included 110 patients with asthma, chronic obstructive pulmonary disease using the inhaler at least one month. Inhaler errors performed during demonstration were evaluated for each patient and entered in the check-lists. We also collected information about co-morbidities, education, mMRC dyspnea score, rate of exacerbations, and performed spirometry.

RESULTS

80.9% of patients used metered-dose inhaler, 20.9% - single-dose and 21.8% - multiple-dose dry powder inhaler, 22.7% - soft-mist inhaler. Inhaler errors were made by 80.9% patients. The mean number of mistakes in metered-dose inhaler use was 2±1.6, single-dose powder inhaler -1.5±1.3, multiple-dose dry powder inhaler - 1.25±1.4, soft-mist inhaler - 0.68±0.7 (=0.003). Age, diagnosis, duration of disease, education level, inhalers usage by relatives have no influence on the inhalation technique. A number of errors was related to female gender (=0.007) and usage of more than 2 inhalers (=0.3, =0.002), previous instruction about inhalation technique (=0.3, =0.001). On the other hand, there were correlations between the number of errors and degree of bronchial obstruction, asthma control, severity of dyspnea by mMRC score, exacerbation rate.

CONCLUSION

Patients with bronchoobstructive diseases perform many inhaler errors, that substantially influences the severity and course of asthma and chronic obstructive pulmonary disease.

摘要

目的

研究使用不同类型吸入器的吸入技术及其对疾病进程的影响。

材料与方法

这项横断面研究纳入了110例哮喘、慢性阻塞性肺疾病患者,这些患者使用吸入器至少1个月。对每位患者在演示过程中出现的吸入器使用错误进行评估,并记录在检查表中。我们还收集了有关合并症、教育程度、mMRC呼吸困难评分、急性加重率的信息,并进行了肺功能测定。

结果

80.9%的患者使用定量气雾剂,20.9%使用单剂量干粉吸入器,21.8%使用多剂量干粉吸入器,22.7%使用软雾吸入器。80.9%的患者存在吸入器使用错误。定量气雾剂使用中的平均错误数为2±1.6,单剂量干粉吸入器为1.5±1.3,多剂量干粉吸入器为1.25±1.4,软雾吸入器为0.68±0.7(P=0.003)。年龄、诊断、病程、教育水平、亲属使用吸入器的情况对吸入技术无影响。错误数量与女性性别(P=0.007)、使用超过2种吸入器(P=0.3,P=0.002)、既往吸入技术指导(P=0.3,P=0.001)有关。另一方面,错误数量与支气管阻塞程度、哮喘控制情况、mMRC评分的呼吸困难严重程度、急性加重率之间存在相关性。

结论

支气管阻塞性疾病患者存在许多吸入器使用错误,这对哮喘和慢性阻塞性肺疾病的严重程度及病程有重大影响。

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