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与秘鲁兰巴耶克三级医院 COVID-19 住院患者死亡相关的因素,在大流行的第一波期间。

Factors associated with mortality in patients hospitalized for COVID-19 admitted to a tertiary hospital in Lambayeque, Peru, during the first wave of the pandemic.

机构信息

Servicio de Geriatría, Departamento de Medicina, Hospital Nacional Almanzor Aguinaga Asenjo, Chiclayo, Peru.

Facultad de Medicina Humana, Universidad de San Martín de Porres, Chiclayo, Peru.

出版信息

PLoS One. 2023 May 11;18(5):e0285133. doi: 10.1371/journal.pone.0285133. eCollection 2023.

DOI:10.1371/journal.pone.0285133
PMID:37167338
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10174592/
Abstract

INTRODUCTION

COVID-19 caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has spread worldwide, becoming a long-term pandemic.

OBJECTIVES

To analyze the factors associated with mortality in patients hospitalized for COVID-19 in a tertiary hospital in the Lambayeque region of Peru.

METHODS

A retrospective cohort study of patients with a diagnosis of COVID-19, hospitalized in a hospital in northern Peru, was conducted from March to September 2020.

RESULTS

Of the 297 patients studied, 69% were women, the mean age was 63.99 years (SD = ±15.33 years). Hypertension was the most frequent comorbidity (36.67%), followed by diabetes mellitus (24.67%) and obesity (8.33%). The probability of survival at 3 days of ICU stay was 65.3%, at 7 days 24.2%, and 0% on day 14. Risk factors associated with mortality in patients hospitalized for COVID-19 are age, male sex, tachypnea, low systolic blood pressure, low peripheral oxygen saturation, impaired renal function, elevated IL-6 and elevated D-dimer.

CONCLUSIONS

Mortality in hospitalized patients with COVID-19 was 51.18 per 100 persons, Mortality was found to be associated with hypertension, type of infiltrating, and sepsis.

摘要

简介

由严重急性呼吸系统综合征冠状病毒 2 型(SARS-CoV-2)引起的 COVID-19 已在全球范围内传播,成为长期大流行。

目的

分析秘鲁兰巴耶克地区一家三级医院住院 COVID-19 患者死亡的相关因素。

方法

对 2020 年 3 月至 9 月期间在秘鲁北部一家医院住院的 COVID-19 患者进行回顾性队列研究。

结果

在 297 名研究患者中,69%为女性,平均年龄为 63.99 岁(SD = ±15.33 岁)。最常见的合并症是高血压(36.67%),其次是糖尿病(24.67%)和肥胖症(8.33%)。入住 ICU 3 天的生存率为 65.3%,7 天为 24.2%,14 天为 0%。与 COVID-19 住院患者死亡相关的危险因素是年龄、男性、呼吸急促、收缩压低、外周血氧饱和度低、肾功能受损、IL-6 和 D-二聚体升高。

结论

COVID-19 住院患者的死亡率为每 100 人 51.18 人,死亡率与高血压、浸润类型和败血症有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc3f/10174592/5dfa94f14288/pone.0285133.g004.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc3f/10174592/5dfa94f14288/pone.0285133.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc3f/10174592/f0b7707ee013/pone.0285133.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc3f/10174592/fb86a8482af9/pone.0285133.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc3f/10174592/8b3663d04c48/pone.0285133.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc3f/10174592/5dfa94f14288/pone.0285133.g004.jpg

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