Department of General Surgery, Xuzhou Kuangshan Hospital, Xuzhou, China.
School of Food and Drug, Xuzhou Polytechnic College of Bioengineering, Xuzhou, China.
Genet Res (Camb). 2023 Apr 30;2023:9923428. doi: 10.1155/2023/9923428. eCollection 2023.
Ovarian metastasis of gastric cancer indicates that the disease has reached the late stage and the opportunity for radical surgery is restricted. However, the clinical characteristics and prognosis of patients with gastric cancer ovarian metastasis (GCOM) remain to be illustrated. Here, we retrieved the information of 780 GCOM cases from the Surveillance, Epidemiology, and End Results (SEERs) database and analyzed their clinicopathological characteristics as well as their survival. According to our data, most GCOM patients showed poor pathological differentiation, advanced T and N stages. The prognostic factors include patients' age, tumor size, surgical resection, and chemotherapy treatment. Of note, the marriage status was also identified as an independent prognostic factor. Besides the identification of prognostic factors, we established nomograms to help predict the overall survival and cancer-specific survival of GCOM, respectively.
胃癌卵巢转移表明疾病已进入晚期，根治性手术机会受限。然而，胃癌卵巢转移（GCOM）患者的临床特征和预后仍需阐明。本研究从监测、流行病学和最终结果（SEER）数据库中检索了 780 例 GCOM 病例的信息，并分析了其临床病理特征和生存情况。根据我们的数据，大多数 GCOM 患者表现出较差的病理分化、较晚的 T 和 N 分期。预后因素包括患者的年龄、肿瘤大小、手术切除和化疗治疗。值得注意的是，婚姻状况也被确定为独立的预后因素。除了确定预后因素外，我们还建立了列线图，分别用于预测 GCOM 的总生存和癌症特异性生存。
