Chauhan Rashi, Singh Amit Kumar, Singh Manisha, Shree Richa, Anand Santosh, Singh Ashok Kumar, Verma Sankalp
Buddha Institute of Dental Science And Hospital, Bihar, Patna; 2Minority Dental College And Research Center, Darbhanga, Bihar, India.
Bioinformation. 2022 Jun 30;18(6):543-546. doi: 10.6026/97320630018543. eCollection 2022.
It is of interest to assess levels of serum cornitine in male tobacco users and also find its correlation with bone mineral density. Assessment for serum cotinine levels was done using commercially available Enzyme Linked Immunosorbent Assay (ELISA Kit). While bone mineral density was measured using bone densitometry through ultrasound in the wrist region. Karl Pearson's coefficient was used to assess correlation between BMD values and serum cotinine (ng/ml) levels. Inter group BMD association was measured using Chi square test. The present study showed that the first 3 groups had a low BMD level compared to control group, indicative of osteopenia. BMD values were lesser for chewers from group II as compared to smokers from group I and individuals using both smoked and smokeless form of tobacco from Group III. In group III (both forms of tobacco), osteopenic individuals were more. Thus, data shows effect of tobacco usage on bone mineral density. Smokeless form of tobacco has relatively serious effects on bone density.
评估男性烟草使用者的血清肉碱水平并找出其与骨矿物质密度的相关性很有意义。使用市售的酶联免疫吸附测定法（ELISA试剂盒）评估血清可替宁水平。而骨矿物质密度则通过手腕部位的超声骨密度测定法进行测量。采用卡尔·皮尔逊系数评估骨密度值与血清可替宁（ng/ml）水平之间的相关性。组间骨密度关联采用卡方检验进行测量。本研究表明，与对照组相比，前三组的骨密度水平较低，表明存在骨质减少。与第一组的吸烟者和第三组同时使用吸烟和无烟烟草形式的个体相比，第二组咀嚼者的骨密度值更低。在第三组（两种烟草形式）中，骨质减少的个体更多。因此，数据显示了烟草使用对骨矿物质密度的影响。无烟烟草形式对骨密度有相对严重的影响。
