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酮粪石：与婴儿开始生酮饮食相关的不良事件

Keto-Bezoar: Adverse Event Related to Initiation of Ketogenic Diet in an Infant.

作者信息

Stegall Cassandra, Evans Melissa C, Hollinger Laura E, Walz Alice A

机构信息

From the Department of Pediatrics, Medical University of South Carolina, Charleston, SC.

Division of Critical Care, Department of Pediatrics, Medical University of South Carolina, Charleston, SC; and.

出版信息

JPGN Rep. 2022 Feb 25;3(2):e179. doi: 10.1097/PG9.0000000000000179. eCollection 2022 May.

DOI:10.1097/PG9.0000000000000179
PMID:37168910
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10158299/
Abstract

The ketogenic diet is frequently used as part of the treatment regimen for pediatric patients with refractory epilepsy. This diet is generally well tolerated, with constipation being the most described side effect. This case highlights a previously undocumented severe complication of a "keto-bezoar" formation related to the initiation of the ketogenic diet in a young infant.

摘要

生酮饮食经常被用作难治性癫痫患儿治疗方案的一部分。这种饮食通常耐受性良好，便秘是最常被描述的副作用。本病例突出了一名幼儿因开始生酮饮食而形成“酮石”这一此前未记录的严重并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f92/10158299/fb046e68f692/pg9-3-e179-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f92/10158299/7ae63c4cd6d5/pg9-3-e179-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f92/10158299/fb046e68f692/pg9-3-e179-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f92/10158299/7ae63c4cd6d5/pg9-3-e179-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f92/10158299/fb046e68f692/pg9-3-e179-g002.jpg

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本文引用的文献

1
Ketogenic diet for infants with epilepsy: A literature review. ketogenic 饮食治疗婴儿癫痫：文献综述。
Epilepsy Behav. 2020 Nov;112:107361. doi: 10.1016/j.yebeh.2020.107361. Epub 2020 Sep 28.
2
The ketogenic diet for infants: How long can you go?婴儿生酮饮食：能坚持多久？
Epilepsy Res. 2020 Aug;164:106339. doi: 10.1016/j.eplepsyres.2020.106339. Epub 2020 May 6.
3
The ketogenic diet in children 3 years of age or younger: a 10-year single-center experience.3 岁及以下儿童的生酮饮食：10 年单中心经验。
Sci Rep. 2019 Jun 19;9(1):8736. doi: 10.1038/s41598-019-45147-6.
4
Fat composition in infant formula contributes to the severity of necrotising enterocolitis.婴儿配方奶粉中的脂肪成分会导致坏死性小肠结肠炎的严重程度增加。
Br J Nutr. 2018 Sep;120(6):665-680. doi: 10.1017/S0007114518001836.
5
Ketogenic Diet Therapy in Infants: Efficacy and Tolerability.婴儿生酮饮食疗法：疗效和耐受性。
Pediatr Neurol. 2018 May;82:13-18. doi: 10.1016/j.pediatrneurol.2017.10.018. Epub 2018 Jan 31.
6
Ketogenic diet therapy in infants less than two years of age for medically refractory epilepsy.生酮饮食疗法用于两岁以下药物难治性癫痫婴儿。
Seizure. 2018 Apr;57:5-7. doi: 10.1016/j.seizure.2018.02.014. Epub 2018 Mar 2.
7
Ketogenic diet and other dietary treatments for epilepsy.生酮饮食及其他癫痫的饮食疗法
Cochrane Database Syst Rev. 2016 Feb 9;2:CD001903. doi: 10.1002/14651858.CD001903.pub3.
8
Introduction of a ketogenic diet in young infants.在小婴儿中引入生酮饮食。
J Inherit Metab Dis. 2002 Oct;25(6):449-60. doi: 10.1023/a:1021238900470.