Caldarelli D D, Rejowski J E, Corey J P
Am J Otol. 1986 May;7(3):210-3.
A 51-year-old woman had sudden profound sensorineural hearing loss (SNHL) in her right ear, followed by profound SNHL in her left ear three weeks later. On subsequent work-up, a diagnosis of systemic lupus erythematosus (SLE) was made on the basis of an antinuclear antibody titer of 1:500 and immunofluorescence below the dermis on skin and muscle biopsy specimens. Treatment with prednisone and cyclophosphamide did not improve the hearing loss. To our knowledge, this is the second reported case of SLE occurring with SNHL and the first reported case of bilateral hearing loss.
一名51岁女性右耳突发严重感音神经性听力损失（SNHL），三周后左耳也出现严重SNHL。在后续检查中，根据抗核抗体滴度为1:500以及皮肤和肌肉活检标本真皮层以下的免疫荧光检查结果，诊断为系统性红斑狼疮（SLE）。泼尼松和环磷酰胺治疗未能改善听力损失。据我们所知，这是第二例报道的SLE伴发SNHL的病例，也是首例报道的双侧听力损失病例。
