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头颈癌挽救性手术的当前方法:全面综述

Current Approaches to Salvage Surgery for Head and Neck Cancer: A Comprehensive Review.

作者信息

Mastronicola Romina, Le Roux Pauline, Casse Aurore, Cortese Sophie, Beulque Emilie, Perna Marco, Dolivet Gilles

机构信息

Institut de Cancérologie de Lorraine ICL, 6 Avenue de Bourgogne, 54519 Vandoeuvre-lès-Nancy, France.

CRAN, CNRS, UMR 7039, Université de Lorraine, 54519 Vandoeuvre-lès-Nancy, France.

出版信息

Cancers (Basel). 2023 May 5;15(9):2625. doi: 10.3390/cancers15092625.

DOI:10.3390/cancers15092625
PMID:37174091
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10177213/
Abstract

Salvage surgeries of head and neck cancer are often complicated and do not always show decent results. This type of procedure is tough on the patient, as many crucial organs can be affected. A long period of reeducation usually follows the surgery because of the need to rehabilitate functions such as speech or swallowing. In order to lighten the journey of the patients, it is important to develop new technologies and techniques to ease the surgery and limit its damages. This seems even more crucial since progress has been made in the past years, allowing more salvage therapy to take place. This article aims at showing the available tools and procedures for salvage surgeries, such as transoral robotic surgery, free-flap surgery, sentinel node mapping, and many others, that help the work of the medical team to operate or obtain a better understanding of the status of the cancer when taken in charge. Yet, the surgical procedure is not the only thing determining the outcome of the operation. The patient themself and their cancer history also play an important part in the care and must be acknowledged.

摘要

头颈癌的挽救性手术通常很复杂,而且效果并不总是理想。这类手术对患者来说很艰难,因为许多重要器官可能会受到影响。由于需要恢复如言语或吞咽等功能,手术后通常需要很长一段时间的再训练。为了减轻患者的痛苦,开发新技术和新技巧以简化手术并减少其损伤非常重要。鉴于过去几年已经取得了进展,使得更多的挽救性治疗得以开展,这一点似乎更为关键。本文旨在展示挽救性手术可用的工具和程序,如经口机器人手术、游离皮瓣手术、前哨淋巴结定位等,这些有助于医疗团队开展手术工作,或在负责治疗时更好地了解癌症状况。然而,手术过程并非决定手术结果的唯一因素。患者自身及其癌症病史在治疗中也起着重要作用,必须予以重视。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17b3/10177213/4f2a6b6f262b/cancers-15-02625-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17b3/10177213/e5abc9737046/cancers-15-02625-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17b3/10177213/942917376b9d/cancers-15-02625-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17b3/10177213/4f2a6b6f262b/cancers-15-02625-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17b3/10177213/e5abc9737046/cancers-15-02625-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17b3/10177213/942917376b9d/cancers-15-02625-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17b3/10177213/4f2a6b6f262b/cancers-15-02625-g003.jpg

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本文引用的文献

1
Current radiotherapy for recurrent head and neck cancer in the modern era: a state-of-the-art review.当代复发性头颈部癌症的放射治疗:现状综述。
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Indocyanine green fluorescence-guided surgery in head and neck cancer: A systematic review.吲哚菁绿荧光引导手术在头颈部肿瘤中的应用:系统评价。
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Role of Navigation in Oral and Maxillofacial Surgery: A Surgeon's Perspectives.导航在口腔颌面外科中的作用:外科医生的观点。
Clin Cosmet Investig Dent. 2021 Apr 15;13:127-139. doi: 10.2147/CCIDE.S299249. eCollection 2021.
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Long-term survival after head and neck cancer surgery with immediate free flap reconstruction.头颈部癌症手术后即刻游离皮瓣重建的长期生存。
Ann Chir Plast Esthet. 2021 Oct;66(5):357-363. doi: 10.1016/j.anplas.2021.02.002. Epub 2021 Apr 3.
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Estimating the risks and benefits before salvage surgery for recurrent head and neck squamous cell carcinoma.评估复发头颈部鳞状细胞癌挽救性手术的风险和获益。
Eur J Surg Oncol. 2021 Jul;47(7):1718-1726. doi: 10.1016/j.ejso.2021.01.022. Epub 2021 Jan 29.
8
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.《全球癌症统计数据 2020:全球 185 个国家和地区 36 种癌症的发病率和死亡率估计》。
CA Cancer J Clin. 2021 May;71(3):209-249. doi: 10.3322/caac.21660. Epub 2021 Feb 4.
9
Lymphoscintigraphy for Sentinel Node Mapping in Head and Neck Cancer.头颈部癌前哨淋巴结作图的淋巴闪烁显像法。
Semin Nucl Med. 2021 Jan;51(1):39-49. doi: 10.1053/j.semnuclmed.2020.07.004. Epub 2020 Aug 2.
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Oral Oncol. 2020 Dec;111:104939. doi: 10.1016/j.oraloncology.2020.104939. Epub 2020 Jul 31.